IRCT20201108049300N1 IRCT 2021-10-02 Yasouj University of Medical Sciences Effect of oral probiotics on the prevention of preterm delivery Evaluation of the effect of oral probiotics on the prevention of preterm delivery in mothers at risk of preterm delivery compared with placebo 2021-09-18 anticipated 120 Complete https://irct.ir/trial/58571 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: The randomization process is done with Random Allocation Soft ware. Randomization is done using the block method. It is an individual randomization unit. Randomization is performed using a table of random numbers and a computer is used to generate a random sequence online. To hide the treatment allocation, the list of treatments is placed in sealed and numbered envelopes (to maintain sequence order). N/A preterm delivery. Intervention 1: Intervention group: Lactofem capsule (500 mg) made by Iranian zist-takhmir Company will be administered orally and daily from the 16 weeks until the end of pregnancy. Intervention 2: Control group: Placebo drug is very similar to group A with the same method, the duration of treatment will be prescribed. The placebo drug will be prepared by a zist-takhmir company similar to probiotics. No - There is not a plan to make this available Justification or reason for not sharing IPD is No more information