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IRCT20101020004976N8 IRCT 2021-09-08 Mashhad University of Medical Sciences The effect of topical probiotic lotion on atopic dermatitis in children Investigation of the effect of topical probiotic lotion on atopic dermatitis in children 2021-09-16 anticipated 30 Complete https://irct.ir/trial/58458 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Simple randomization with table of random numbers available at ''www.randomization.com'' website will be used. Numbers will be placed in sealed envelopes and each envelope is assigned to one participant placing them in one of the two groups control and intervention, Blinding description: In this study, participants are not aware of the type of treatment and the intervention. Also, outcome assessors are unaware of the grouping. Patients in the control group receive placebo drug. 3 atopic dermatitis. Intervention 1: Intervention group: In this group, patients with atopic dermatitis receive a lotion containing lactobacillus reuteri strain JCM 1112 (produced by the school of pharmacy of Mashhad University of Medical Sciences) twice a day for 4 weeks for their lesions. Standard treatments for eczema including skin moisturizers and topical steroids, will be performed on all patients. Intervention 2: Control group: In this group, patients with atopic dermatitis are treated with a placebo drug which is a lotion (produced by the school of pharmacy of Mashhad University of Medical Sciences) that looks like the one in the intervention group twice a day for 4 weeks for their lesions. Standard treatments for eczema including skin moisturizers and topical steroids, will be performed on all patients. Yes - There is a plan to make this available What will be shared: All data can be shared after patients are made unidentifiable. When: Data can be accessible 6 months after results are published. To whom: Data can be accessible through an email to the corresponding author. Conditions: Data will be available for researchers in universities and other scientific institutes. Where to obtain: After sending a request email to the corresponding author, data will be sent in 1 month. How to obtain: Carrying out analysis on data is permitted. Comments:
public Hamid Ahanchian
Ghaem hospital, Ahmad Abad blvd, Mashhad iran
Mashhad Iran (Islamic Republic of) 9176999311 +98 51 1801 2522 ahanchianh@mums.ac.ir Mashhad University of Medical Sciences scientific Hamid Ahanchian
Ghaem hospital, Ahmad Abad blvd, Mashhad iran
Mashhad Iran (Islamic Republic of) 9176999311 +98 51 1801 2522 ahanchianh@mums.ac.ir Mashhad University of Medical Sciences Iran (Islamic Republic of) Infants and children with atopic dermatitis 1 day 18 years Both Having other allergic diseases Having other skin diseases L20 Atopic dermatitis Treatment - Drugs Placebo Intervention group: In this group, patients with atopic dermatitis receive a lotion containing lactobacillus reuteri strain JCM 1112 (produced by the school of pharmacy of Mashhad University of Medical Sciences) twice a day for 4 weeks for their lesions. Standard treatments for eczema including skin moisturizers and topical steroids, will be performed on all patients. Control group: In this group, patients with atopic dermatitis are treated with a placebo drug which is a lotion (produced by the school of pharmacy of Mashhad University of Medical Sciences) that looks like the one in the intervention group twice a day for 4 weeks for their lesions. Standard treatments for eczema including skin moisturizers and topical steroids, will be performed on all patients. Severity of lesions. Timepoint: At the beginning of the study, at the end of the study in the fourth week and in the first and second months after the end of the study. Method of measurement: Severity Scoring of Atopic Dermatitis (SCORAD). Mashhad University of Medical Sciences Approved 2021-06-15 Ethics Committee of Mashhad University of Medical Sciences Central Building of Mashhad University of Medical Sciences (Ghorshi), Daneshgah 16, Daneshgah street Mashhad Razavi Khorasan Iran (Islamic Republic of)