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IRCT201706015381N12 IRCT 2017-06-21 Vice chancellor research for Babol University of Medical Sciences The Effect Of Ondansetron on maternal hypotension prevention during elective cesarean section Efficacy of intravenous ondansetron in preventing hypotension in patients undergoing elective cesarean section 2017-01-20 anticipated 80 Complete https://irct.ir/trial/5779 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Other design features: All Patients by using random numbers, they were divided into two groups. N/A Maternal hypotension. Intervention 1: Control group: 2 mm distilled water was injected intravenously before spinal anesthesia. Intervention 2: Intervention group: 4 mg ondansetron ( Norman/Italy) was injected intravenously before spinal anesthesia.
public Dr. Nadia Banihashem
Rouhani Hospital, Ganjafrooz Street, Babol
Babol Iran (Islamic Republic of) +98 11 3223 8284 nbanihashem@yahoo.com Babol University of Medical Sciences scientific Dr.Nadia Banihashem
Rouhani Hospital, Ganjafrooz Street, Babol
Babol Iran (Islamic Republic of) +98 11 3223 8284 nbanihashem@yahoo.com Babol University Of Medical Sciences Iran (Islamic Republic of) Inclusion Criteria: Pregnant women (18 to 35 years old) Candidate for elective cesarean section, In class I physical health classification of the American Society of Anesthesia. All women had singleton term pregnancies. Exclusion Criteria: Mothers with a history of hypertension؛ Diabetes؛ cardiovascular and cerebral diseases؛ known fetal anomaly؛ any kind of contraindications for spinal anesthesia؛ psychosomatic Disorder؛ Patients weighting over 100 Kg and Height less than 150 cm and those with difficult tracheal intubation 18 years 35 years Female O26.5 Maternal hypotension syndrome Prevention Prevention Control group: 2 mm distilled water was injected intravenously before spinal anesthesia Intervention group: 4 mg ondansetron ( Norman/Italy) was injected intravenously before spinal anesthesia Maternal blood presure. Timepoint: Maternal blood pressure was monitored and recorded every two minutes for the first 15 minutes following spinal anesthesia, and then every 5 minutes until completion of surgery. Method of measurement: Non invasive blood presure cuff. Maternal heart rate. Timepoint: during surgery. Method of measurement: With cardiac monitoring and heart rate. Neonatal arterial blood gas. Timepoint: After Surgery. Method of measurement: Arterial blood gas samples. Neonatal apgar score. Timepoint: 1 and 5 minutes after surgery. Method of measurement: Cheklist/ examination/ observation. Vice chancellor research for Babol University of Medical Sciences Approved 2017-01-09 Ethics committee of Babol University Of Medical Sciences Babol University of Medical Sciences, Ganjafrooz Street, Babol Babol Iran (Islamic Republic of)