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IRCT20140415017288N8 IRCT 2021-09-07 Islamic Azad University high-intensity interval training and aloe vera supplementation The effect of a high-intensity interval training and aloe vera supplementation on some plasma adipokines in type 2 diabetic 2021-11-16 anticipated 44 Complete https://irct.ir/trial/57340 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Health service research, Randomization description: In this research, subjects are selected Simple randomization by random allocation rule. After determining the sample size, they will be equally divided into 4groups (1- Control, 2- Exercise, 3- supplementation and 4- Exercise + supplementation ). Using the lottery method, the names of the subjects are written on separate papers and placed in a container, then the names of the subjects are randomly taken out and placed in the intervention groups or placebo, respectively, Blinding description: Each capsule will contain 100 mg of aloe vera gel powder, and each subject will receive one capsule in the morning immediately after waking up and one capsule after dinner, and the control and exercise groups will receive the same amount of placebo. Starch is used as a placebo. 3 Type 2 Diabetes. Intervention 1: Control group: (in this group we have not any intervention during 12 weeks, and will consider this group as placebo). Intervention 2: Intervention group: High Intensity Periodic Exercise Group (Training protocol of up to 60 cycles per 20-minute session (including 8 seconds of fast pedaling (about 80% of maximum heart rate (HRmax)) followed by gentle pedaling (20-30 rpm) for 12 seconds , To facilitate acceleration and limit the stagnation of the bicycle wheel, the selected resistance will be very low (almost zero). Intervention 3: Intervention group: Aloe vera supplement group Each capsule will contain 100 mg of aloe vera gel powder, and each subject will receive one capsule in the morning immediately after waking up and one capsule after dinner. Intervention 4: Intervention group: High Intensity Periodic Exercise Group - Aloe Vera Supplement (In this group the Simultaneous intervention, aloe vera gel and training, will treat with the same protocol that describe at the previous part). Yes - There is a plan to make this available What will be shared: The report is submitted to the research department of the university. Also published as a paper When: Since 2021 To whom: All researchers Conditions: Citing references Where to obtain: Scientific bases and Ayatollah Amoli Branch, Islamic Azad University, amol, Iran How to obtain: Maximum one week Comments:
public Ahmad Abdi
Ayatollah Amoli Branch, Islamic Azad University
Amol Iran (Islamic Republic of) 461671618 +98 11 4321 7126 A.abdi@iauamol.ac.ir Islamic Azad University scientific Alireza Barari
Ayatollah Amoli Branch, Islamic Azad University
Amol Iran (Islamic Republic of) 4616716187 +98 11 4321 7126 Alireza54.barari@gmail.com Islamic Azad University Iran (Islamic Republic of) Type 2 diabetes (people with a history of more than twice the fasting glucose above 126 mg / dL with HbA1c above 6.5% and under the supervision of a physician at the time of the study) . Subjects were asked to complete a questionnaire of readiness to start sports. Lack of cardiovascular Lack of musculoskeletal Lack of metabolic diseases limited exercise lack of high blood pressure lack of a history of regular exercise during the past six months lack of insulin 25 years 40 years Male Use of drugs that lower blood pressure and blood lipids Exclusion criteria included a history of serious diabetic complications (such as proliferative diabetic retinopathy, stage 3 or subsequent overt nephropathy, diabetic ketoacidosis or severe diabetic neuropathy) fasting glucose above 270 mg / dL malaise Hereditary absorption of glucose and galactose or renal glycosuria E11 Type 2 diabetes mellitus Placebo Treatment - Other Treatment - Other Treatment - Other Control group: (in this group we have not any intervention during 12 weeks, and will consider this group as placebo) Intervention group: High Intensity Periodic Exercise Group (Training protocol of up to 60 cycles per 20-minute session (including 8 seconds of fast pedaling (about 80% of maximum heart rate (HRmax)) followed by gentle pedaling (20-30 rpm) for 12 seconds , To facilitate acceleration and limit the stagnation of the bicycle wheel, the selected resistance will be very low (almost zero). Intervention group: Aloe vera supplement group Each capsule will contain 100 mg of aloe vera gel powder, and each subject will receive one capsule in the morning immediately after waking up and one capsule after dinner. Intervention group: High Intensity Periodic Exercise Group - Aloe Vera Supplement (In this group the Simultaneous intervention, aloe vera gel and training, will treat with the same protocol that describe at the previous part). Metrenal. Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods. Catspin. Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods. Total Antioxidant Capacity. Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods. Malondialdehyde. Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods. Islamic Azad University Approved 2020-09-13 Ethics Committee of Marvdasht Branch of Azad University Three kilometers of Persepolis Boulevard, Islamic Azad University of Marvdasht Marvdasht Fars Iran (Islamic Republic of)