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IRCT20200408046987N4 IRCT 2022-01-27 Qazvin University of Medical Sciences The effect of Resveratrol on some biochemical and hormonal factors The effect of Resveratrol on some biochemical and hormonal factors in university staff 2022-02-04 anticipated 80 Complete https://irct.ir/trial/56958 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Health service research, Randomization description: In this study, a simple randomization method is used and a list of random numbers is created with Randomizer software. The software randomly divides this list from 1 to 80 between the control and intervention groups. Depending on the order of patients' referrals, they are given a number from 1 to 80 from the list of random numbers, and based on the list created by the software, which assigns each number to one of the two control and intervention groups, people enter the intervention or control group. be, Blinding description: Participants will be given medication or placebo after signing the consent form. The therapist and outcome assessor will not know the type of treatment, and the data analyzer will only know the group numbers. 3 Metabolic syndrome. Intervention 1: Intervention group: People in this group take Resveratrol (An active compound of acetylene phytoalexin) capsule supplements once a day before meals for a month. Intervention 2: Control group: People in this group take one 1000 mg capsule containing wheat flour instead of Resveratrol every day for a month before a meal. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is .
public Dr. Nematollah Gheibi
Bahonar Blvd
Qazvin Iran (Islamic Republic of) 3419915315 +98 28 3332 8212 ngheibi@qums.ac.ir Qazvin University of Medical Sciences scientific Dr. Nematollah Gheibi
Bahinar Blvd
Qazvin Iran (Islamic Republic of) 3419915315 +98 28 3332 8212 ngheibi@qums.ac.ir Qazvin University of Medical Sciences Iran (Islamic Republic of) People between 18 to 50 years old Complete consent of individuals to participate in the study Having a BMI of 25 to 30 kg/m² 18 years 50 years Both People having any allergies to the drug People with diabetes People with a history of high fat under treatment People taking vitamins and supplements People taking herbal medicines Patients with a history of inflammatory disease being treated People with known liver and kidney disease People with known lipid disease People treated with corticosteroids, aspirin and anti-lipids and hormonal drugs, hyperthyroidism and hypothyroidism People on drug treatment related to metabolic syndrome Treatment - Drugs Placebo Intervention group: People in this group take Resveratrol (An active compound of acetylene phytoalexin) capsule supplements once a day before meals for a month. Control group: People in this group take one 1000 mg capsule containing wheat flour instead of Resveratrol every day for a month before a meal. Measurement of fasting Insulin. Timepoint: Before starting intervention and one month after intervention. Method of measurement: At the beginning and end of the study, it will be measured by Snible kit. Measuring the mass of fat accumulated in the body. Timepoint: Before starting intervention and one month after intervention. Method of measurement: At the beginning and end of the study, the amount of accumulated fat will be measured with a digital scale. Measurement of Follicle Stimulating Hormone. Timepoint: Before starting intervention and one month after intervention. Method of measurement: At the beginning and end of the study, it will be measured by Snible kit. Measurement of Luteinizing hormone. Timepoint: Before starting intervention and one month after intervention. Method of measurement: At the beginning and end of the study, it will be measured by Snible kit. Measurement of Dehydroepiandroterone. Timepoint: Before starting intervention and one month after intervention. Method of measurement: At the beginning and end of the study, it will be measured by Snible kit. Measurement of Anti Mullerian hormone. Timepoint: Before starting intervention and one month after intervention. Method of measurement: At the beginning and end of the study, it will be measured by kit. Measurement of Insulin-like growth factor 1. Timepoint: Before starting intervention and one month after intervention. Method of measurement: At the beginning and end of the study, it will be measured by kit. Measurement of Interleukin 6. Timepoint: Before starting intervention and one month after intervention. Method of measurement: At the beginning and end of the study, it will be measured by kit. Measurement of Self-monitoring of blood glucose. Timepoint: Before starting intervention and one month after intervention. Method of measurement: At the beginning and end of the study, it will be measured by kit. Measurement of Testosterone. Timepoint: Before starting intervention and one month after intervention. Method of measurement: At the beginning and end of the study, it will be measured by kit. Measurement of White Blood Cell. Timepoint: Before starting intervention and one month after intervention. Method of measurement: At the beginning and end of the study, it will be measured by cell counter. Measurement of Lymphocyte. Timepoint: Before starting intervention and one month after intervention. Method of measurement: At the beginning and end of the study, it will be measured by cell counter. Measurement of Neutrophil. Timepoint: Before starting intervention and one month after intervention. Method of measurement: At the beginning and end of the study, it will be measured by cell counter. Measurement of Platelet. Timepoint: Before starting intervention and one month after intervention. Method of measurement: At the beginning and end of the study, it will be measured by cell counter. Measurement of Body Mass Index. Timepoint: Before starting intervention and one month after intervention. Method of measurement: Weight (in kilograms) Divided by Height (in meters to the power of 2). Measurement of High-Sensitivity C-Reactive Protein. Timepoint: Before starting intervention and one month after intervention. Method of measurement: At the beginning and end of the study, it will be measured by Rosh kit (in mg/dL). Measurement of Low-density lipoprotein. Timepoint: Before starting intervention and one month after intervention. Method of measurement: At the beginning and end of the study, it will be measured by kit. Measurement of High-density lipoprotein. Timepoint: Before starting intervention and one month after intervention. Method of measurement: At the beginning and end of the study, it will be measured by kit. Measurement of Triglyceride. Timepoint: Before starting intervention and one month after intervention. Method of measurement: At the beginning and end of the study, it will be measured by kit. Measurement of Total Antioxidant. Timepoint: Before starting intervention and one month after intervention. Method of measurement: At the beginning and end of the study, it will be measured by kit. Measurement of Fasting Blood Sugar. Timepoint: Before starting intervention and one month after intervention. Method of measurement: At the beginning and end of the study, it will be measured by kit. Measurement of Homeostatic Model Assessment for Insulin Resistance. Timepoint: Before starting intervention and one month after intervention. Method of measurement: At the beginning and end of the study, it will be measured by kit. Qazvin University of Medical Sciences Approved 2021-03-15 Qazvin university of medical sciences Bahonar Blvd Qazvin Qazvin Iran (Islamic Republic of)