]>
IRCT20130311012782N56 IRCT 2021-07-12 Yazd University of Medical Sciences The effect of adding vitamin C tablets to the treatment regimen of patients with major depressive disorder The effect of adding oral vitamin C to standard treatment of major depressive disorder 2021-08-23 anticipated 90 Complete https://irct.ir/trial/56415 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Patients are distributed in two groups by simple random allocation method. To do this, the letter A is written on 45 cards and the letter B is written on 45 cards, and all the cards are placed in a box and mixed well. Patients take a card out of the box when they visit and the patient is assigned to the intervention or control group according to what is written on the card, Blinding description: The study is done in two blinds. Patients and the person evaluating the outcome of treatment are unaware of the type of medication used by patients. Drugs are prepared in similar packages and coded by the project manager and are provided to patients for consumption. 3 Major Depressive Disorder. Intervention 1: Intervention group: Daily administration of 500 mg of vitamin C tablets twice a day, in addition to routine treatment of major depressive disorder for two months. Intervention 2: Control group: Prescribe a placebo similar to 500 mg vitamin C tablets twice a day for two months. No - There is not a plan to make this available Justification or reason for not sharing IPD is The project belongs to a government organization and it is not possible to share it.
public Mohamad Nadi Sakhvidi
Shohadaye gomnam street
Yazd Iran (Islamic Republic of) 8434193474 +98 31 3669 2174 nadi.sakhvidi@ssu.ac.ir Yazd University of Medical Sciences scientific Reza Bidaki
Shohadaye Gomnam street
Yazd Iran (Islamic Republic of) 8434193474 +98 31 3669 2174 r_bidaki@med.ssu.ac.ir Yazd University of Medical Sciences Iran (Islamic Republic of) Having major depressive disorder Patient consent to participate in the study Minimum literacy Has a high level of consciousness Has suitable conditions for completing the questionnaire no limit no limit Both Drug addiction Underlying diseases such as diabetes, cardiovascular, lung, cancer Major changes in diet in recent months Verbal and auditory problems in which they are unable to communicate Antioxidant use one month before enrollment, F32 Major depressive disorder, single episode Treatment - Drugs Treatment - Drugs Intervention group: Daily administration of 500 mg of vitamin C tablets twice a day, in addition to routine treatment of major depressive disorder for two months. Control group: Prescribe a placebo similar to 500 mg vitamin C tablets twice a day for two months Intensity of Major Depressive Disorder. Timepoint: Before the intervention, one month and two months after the start of the intervention. Method of measurement: Using the Hamilton Questionnaire. Yazd University of Medical Sciences Approved 2021-02-09 Ethics committee of Shahid Sadughi University of Medical Sciences Shohadaye Gomnam street Isfahan Isfehan Iran (Islamic Republic of)