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IRCT20141220020377N5 IRCT 2021-10-02 Zahedan University of Medical Sciences Comparison of effectiveness of the bioadhesive pastes curcumin and topical corticosteroid for the treatment of Aphthous Stomatitis Comparison of effectiveness of the bioadhesive pastes curcumin and topical corticosteroid for the treatment of Aphthous Stomatitis 2021-09-09 anticipated 30 Complete https://irct.ir/trial/56405 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Samples are selected by available and non-probabilistic methods and from among them, patients who meet the inclusion criteria will be selected. Then patients will be divided into two groups of control and intervention by simple random method (code is assigned to each sample) and using SPSS statistical software, Blinding description: How to use each drug was typed in a container containing an anonymous drug, in an opaque envelope. Each envelope was given to the patient at random. The name of the drug was specified as A and B and was written in the questionnaire on which the test results of the patients were recorded by the researcher. So that it can be analyzed only by the statistics consultant at the end of the research. 3 Recurrent oral aphthae. Intervention 1: Control: Triamcinolone in oral base Ointment (Triadent), topical use in oral mucosa ulcer, 3 time/day, after meal, for 10 days. Intervention 2: Intervention: Curcumin Gel-topical use in oral mucosa ulcer, 3 time/day, after meal for 10 days. Yes - There is a plan to make this available What will be shared: No- There is no plan to make this available at the present time When: starting 10 months after publication To whom: Academic researchers Conditions: It is permitted to use the data in other studies with reference. Where to obtain: Nosratzehi@zaums.ac.ir How to obtain: Sending email to authors Comments:
public Tahereh Nosratzehi
Oral medicine department, faculty of dentistry, Azadegan street,Zahedan
Zahedan Iran (Islamic Republic of) 981675534 +98 54 3411 3041 Nosratzehim@yahoo.com Zahedan University of Medical Sciences scientific Tahereh Nosratzehi
Oral medicine department, faculty of dentistry, Azadegan street,Zahedan
Zahedan Iran (Islamic Republic of) 981655534 +98 54 3411 3041 Nosratzehim@yahoo.com Zahedan University of Medical Sciences Iran (Islamic Republic of) Patients with RAS symptoms for less than 1 day 12 years 79 years Both The patients who did not sign the letter of informed consent Patient with hypertension (greater than 80/130) cases suspected of Behcet's syndrome, inflammatory bowel disease. Pregnant or lactating women Patients with Diabetes Patients Use of systemic aphthous treatment (over the past three months) and topical treatment during the procedure Atypical aphthous cases Patients with RAS symptoms for more than 1 day K12.0 Recurrent oral aphthae Treatment - Drugs Treatment - Drugs Control: Triamcinolone in oral base Ointment (Triadent), topical use in oral mucosa ulcer, 3 time/day, after meal, for 10 days Intervention: Curcumin Gel-topical use in oral mucosa ulcer, 3 time/day, after meal for 10 days Pain sensation. Timepoint: before starting study,days 1,4 ,7 ,10. Method of measurement: Use of visual analoge scale (VAS) from 0- 10, 0: no pain. Recurrent aphthous ulcers. Timepoint: days 1,4,7,10. Method of measurement: Measuring of ulcers by ruler. Zahedan University of Medical Sciences Approved 2020-06-30 Ethics Committee Research Vice Chacellorship of Zahedan University of Medical Sciences Oral medicine department, faculty of dentistry, Azadegan street,Zahedan Zahedan Sistan-va-Balouchestan Iran (Islamic Republic of)