IRCT20210209050313N1 IRCT 2021-05-20 Tehran University of Medical Sciences Comparison of two antibiotic regimens in eradicating Helicobacter pylori Comparison of triple treatment regimen containing levofloxacin with triple treatment regimen containing clarithromycin in the first line of treatment of patients with Helicobacter pylori infection referred to the clinic of Imam Khomeini Hospital during 2021-2022. 2021-07-23 anticipated 130 Complete https://irct.ir/trial/56140 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: According to the list, he receives one of two antibiotic regimens. The random list in the clinic is numbered from 1 to 130. In front of each number, one of the antibiotic regimens is written and the patients receive the intervention group or the control group according to the list of one of the two regimens. The list consists of four blocks, in each block, there are two intervention groups and two control groups that are randomly arranged inside the block. The blocks themselves were also randomly placed in the list. Random allocation at each stage is done by the methodologist. 3 Helicobacter pylori infection. Intervention 1: Intervention group: Levofloxacin 500 mg daily, amoxicillin 1 g twice daily and omeprazole 20 mg twice daily for 10 days, then omeprazole 20 mg daily for 4 weeks. Intervention 2: Control group: clarithromycin 500 mg, amoxicillin 1 g and omeprazole 20 mg all twice a day for 10 days then 4 weeks daily omeprazole 20 mg. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no more information