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IRCT20210129050174N1 IRCT 2021-12-20 Mashhad University of Medical Sciences The effect of intrathecal sufentanil on analgesia of gastrointestinal cancer surgeries Use high dose of intrathecal sufentanil for intraoperative and postoperative pain relife in gastrointestinal cancers surgeries 2021-05-22 anticipated 50 Complete https://irct.ir/trial/55903 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: People who are going to enter the study,are devided into ten groups of five by blocked randomization method. The first group of five is assigned to the intervention or control group by heads or tails method.The next five person groups will be placed in the intervention or control group alternately according to the first group, Blinding description: Data analyzer are kept blind to assignment to study groups and information is provided to them at the end of the project for analysis. 3 Pain relife in gastrointestinal cancers surgeries. Intervention 1: In the intervention group, immediately before induction of anesthesia, intrathecally received 0.2 micrograms per kilogram of weight of sufentanil (Caspian or Aburihan) and did not receive intravenous opioids during induction of anesthesia. During surgery with due attention to vital signs (20% increase in systolic blood pressure or heart rate compared to baseline values) and also after surgery by monitoring the patient in terms of expressing the first complaint of pain according to the pain scale Numerical and achieving score 3 In the pain table (according to the attached checklist) the need for re-administration of analgesic drug was assessed. Intervention 2: Control group: They receive 0.3 micrograms per kilogram of intravenous sufentanil weight. Yes - There is a plan to make this available What will be shared: The main outcome of the study is shared. When: Access starts from Mehr 1401 To whom: Researchers working in academic and scientific institutions Conditions: Use the data for further studies Where to obtain: Dr. Seyyed Alireza Bamshki - Anesthesiology Department of Imam Rez Hospital How to obtain: Submit a request via email to Dr. Seyed Alireza Bamshki bameshkiar@mums.ac.ir Comments:
public Seyyed Alireza Bameshki
Anesthesiology Department Office, 610 building,Imam Reza hospital
Mashhad Iran (Islamic Republic of) 9137913316 0098513858387 bameshkiar@mums.ac.ir Mashhad University of Medical Sciences scientific Seyyed Alireza Bameshki
Anesthesiology Department Office,610 building,Imam Reza Hospital
Mashhad Iran (Islamic Republic of) 9137913316 +98 51 3858 3878 bameshkiar@mums.ac.ir Mashhad University of Medical Sciences Iran (Islamic Republic of) Iran (Islamic Republic of) Adults who are between 18-75 years old Informed consent for participation in project Candidate for gastrointestinal cancers surgeries 18 years 75 years Both No addiction No history af allergy to sufentanil or other drugs G89.18 Other acute postprocedural pain Treatment - Drugs Treatment - Surgery In the intervention group, immediately before induction of anesthesia, intrathecally received 0.2 micrograms per kilogram of weight of sufentanil (Caspian or Aburihan) and did not receive intravenous opioids during induction of anesthesia. During surgery with due attention to vital signs (20% increase in systolic blood pressure or heart rate compared to baseline values) and also after surgery by monitoring the patient in terms of expressing the first complaint of pain according to the pain scale Numerical and achieving score 3 In the pain table (according to the attached checklist) the need for re-administration of analgesic drug was assessed. Control group: They receive 0.3 micrograms per kilogram of intravenous sufentanil weight. Pain score in pain numerical scale. Timepoint: At the beginning of surgery and every twenty minutes until the end of surgery. Method of measurement: Pain numerical scale. Mashhad University of Medical Sciences Approved 2020-11-18 Ethics committee of Mashhad University of Medical Sciences No 111,Jalal Al Ahmad 10, Jalal Al Ahmad Blvd. Mashhad Razavi Khorasan Iran (Islamic Republic of)