<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20210404050844N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2021-06-03</date_registration>
      <primary_sponsor>Islamic Azad University</primary_sponsor>
      <public_title>The effect of Aspirin on bleeding of tooth</public_title>
      <acronym></acronym>
      <scientific_title>The effect of Aspirin on bleeding after tooth extraction</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2021-05-31</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>40</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/55362</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Not randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Health service research.</study_design>
      <phase>N/A</phase>
      <hc_freetext>Tooth bleeding rate.</hc_freetext>
      <i_freetext>Intervention 1: The controller and the patient will be blind to the study groups. In  case groups, local anesthesia is first performed by injecting Carpol 1.8 cc, containing 3% mp and cocaine.(2.7 to 3.6 cc of MPa and Vaccaine are injected into all patients) and then the tooth is removed in place with the help of forceps and alveolar in a standard way. . After extracting the tooth, a gauze is placed in the extracted tooth for 10 minutesوThe desired area is examined. Bleeding that stops within 10 minutes or less is considered normal. Bleeding that stops within 30 minutes or less is considered moderate. Bleeding that lasts more than 30 minutes and using a collagen sponge, suture, or gas pressure soaked in tranexamic acid (10% transamine, 250 mg / 2.5 Ml) is considered as severe and at the end the bleeding time is recorded. Intervention 2: Control group: The controller and the patient will be blind to the study groups. In  control groups, local anesthesia is first performed by injecting Carpol 1.8 cc, containing 3% mp and cocaine.(2.7 to 3.6 cc of MPa and Vaccaine are injected into all patients) and then the tooth is removed in place with the help of forceps and alveolar in a standard way. . After extracting the tooth, a gauze is placed in the extracted tooth for 10 minutesوThe desired area is examined. Bleeding that stops within 10 minutes or less is considered normal. Bleeding that stops within 30 minutes or less is considered moderate. Bleeding that lasts more than 30 minutes and using a collagen sponge, suture, or gas pressure soaked in tranexamic acid (10% transamine, 250 mg / 2.5 Ml) is considered as severe and at the end the bleeding time is recorded.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Yes - There is a plan to make this available</results_IPD_plan>
      <results_IPD_description>What will be shared:
all data

When:
6 months after printing the results

To whom:
oll of people

Conditions:
researcher

Where to obtain:
Tehran Azad Dental School. Zahra Mirgonjani 
dr.zahra.mirgonjani@gmail .com

How to obtain:
send maill

Comments:
</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Fina Navi</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Pasdaran Av , Neyestan9, dental school</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>1698749511</zip>
        <telephone>+98 21 6641 1657</telephone>
        <email>FINA-NAVI@YAHOO.COM</email>
        <affiliation>Islamic Azad University</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Fina Navi</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Pasdaran Av, Neyestan9, dental school</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>1698749511</zip>
        <telephone>+98 21 6641 1657</telephone>
        <email>FINA-NAVI@yahoo.com</email>
        <affiliation>Islamic Azad University</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>Patients who use to Aspirin80mg/day
Patients  without use Aspirin
Patients who need to extract teeth 6 or 7</inclusion_criteria>
      <agemin>18 years</agemin>
      <agemax>60 years</agemax>
      <gender>Both</gender>
      <exclusion_criteria>Thrombocytopenia
Alcohol and drug addiction
Consumer of other anticoagulants
Kidney and liver dysfunction
Patients receiving nonsteroidal anti-inflammatory drugs
Periodontal tooth disease
Patients need to have their teeth extracted surgically</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code></hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword></hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Treatment - Drugs</i_code>
      <i_code>Treatment - Drugs</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>The controller and the patient will be blind to the study groups. In  case groups, local anesthesia is first performed by injecting Carpol 1.8 cc, containing 3% mp and cocaine.(2.7 to 3.6 cc of MPa and Vaccaine are injected into all patients) and then the tooth is removed in place with the help of forceps and alveolar in a standard way. . After extracting the tooth, a gauze is placed in the extracted tooth for 10 minutesوThe desired area is examined. Bleeding that stops within 10 minutes or less is considered normal. Bleeding that stops within 30 minutes or less is considered moderate. Bleeding that lasts more than 30 minutes and using a collagen sponge, suture, or gas pressure soaked in tranexamic acid (10% transamine, 250 mg / 2.5 Ml) is considered as severe and at the end the bleeding time is recorded.</i_keyword>
      <i_keyword>Control group: The controller and the patient will be blind to the study groups. In  control groups, local anesthesia is first performed by injecting Carpol 1.8 cc, containing 3% mp and cocaine.(2.7 to 3.6 cc of MPa and Vaccaine are injected into all patients) and then the tooth is removed in place with the help of forceps and alveolar in a standard way. . After extracting the tooth, a gauze is placed in the extracted tooth for 10 minutesوThe desired area is examined. Bleeding that stops within 10 minutes or less is considered normal. Bleeding that stops within 30 minutes or less is considered moderate. Bleeding that lasts more than 30 minutes and using a collagen sponge, suture, or gas pressure soaked in tranexamic acid (10% transamine, 250 mg / 2.5 Ml) is considered as severe and at the end the bleeding time is recorded.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Percentage of people with bleeding for more than 30 minutes. Timepoint: Measure bleeding in less than 10 minutes. Less than 30 minutes and more than 30 minutes. Method of measurement: View.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome></sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>not</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2021-03-08</approval_date>
        <contact_name>Ethics Committee of the School of Dentistry - Islamic Azad University of Medical Sciences, Tehran</contact_name>
        <contact_address>Psadaran Av, neyestan9, dental school Tehran Tehran Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
