IRCT138807121310N4 IRCT 2010-03-31 Kermanshah University of Medical Sciences The effect of intrathecal Midazolam in the severity of pain in Cesarean Section: A randomized controlled trial‎ The effect of intrathecal Midazolam in the severity of pain in Cesarean Section: A randomized controlled trial‎ 2007-12-10 anticipated 124 Complete https://irct.ir/trial/551 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. 2 Pain in caesarean section. Intervention 1: The intervention group(62 patients) will received Bupivacaine (12.5 mg) plus intrathecal Midazolam (0.13 mg/kg) intratechally. Intervention 2: Bupivacaine (12.5 mg) plus normal saline (0.5-1 ml) will used in control group (62 patients),intratechally.

public Ali karbasfrushan, MD

Department of Anesthesiology, Imam Reza Hospital, Kermanshah University of Medical Sciences

Kermanshah Iran (Islamic Republic of) 6718818838 +98 918 137 0447 ali_karbasfrushan@yahoo.com ‏ ‏ Kermanshah University of Medical Sciences scientific Ali karbasfrushan, MD

Department of Anesthesiology, Imam Reza Hospital, Kermanshah University of Medical Sciences

Kermanshah Iran (Islamic Republic of) 6718818838 +98 918 137 0447 ali_karbasfrushan@yahoo.com ‏ ‏ Department of Anesthesiology, Imam Reza Hospital, Kermanshah University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria included: No presence of severe spinal lesion, No presence of abscess or infection of skin and soft tissue in the location of needle insertion, No presence of sever anxiety and restlessness, No presence of Central Nervous System lesion, No presence of peripheral nerve lesion, No presence of significant mental disorders or drug abuse, Age 18-45 year. Exclusion criteria: severe spinal lesion, abscess or infection of skin and soft tissue in the location of needle insertion, sever anxiety and restlessness, Central Nervous System lesion, presence of peripheral nerve lesion, presence of significant mental disorders or drug abuse. Age less than 18 or more than 45 years old. 18 years 45 years Female O82.0 Delivery by elective caesarean section Treatment - Drugs Placebo The intervention group(62 patients) will received Bupivacaine (12.5 mg) plus intrathecal Midazolam (0.13 mg/kg) intratechally. Bupivacaine (12.5 mg) plus normal saline (0.5-1 ml) will used in control group (62 patients),intratechally. Severity of pain. Timepoint: 5 min, 15 min, 30 min 1 hour, 2 hour and 4 hour aftercaesarean section. Method of measurement: Verbal Numerical Rating Scale. Kermanshah University of Medical Sciences Approved 2007-06-02 Kermanshah University of Medical Sciences‎ Kermanshah University of Medical Sciences‎ Kermanshah Iran (Islamic Republic of)