]>
IRCT20210310050660N1 IRCT 2021-04-01 Qazvin University of Medical Sciences Evaluation of Cannabidiol effect in treatment of patients with Obsessive-Compulsive Disorder OCD Evaluation of Cannabidiol effect as adjunctive therapy on symptoms of patients with Obsessive-Compulsive Disorder 2021-04-04 anticipated 40 Complete https://irct.ir/trial/55020 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Patients are divided into two treatment groups A and B using the balance block method (Balance block randomization), the size of each block is 6 and the total number of blocks is 10. Balanced randomization allocation method is used for participants in a randomized controlled clinical trial study, Blinding description: Patients are unaware of their treatment, and medications are given in asymptomatic packages to the clinician who is not aware of the patient's treatment. 3 Obsessive compulsive disorder. Intervention 1: Intervention group: In addition to standard treatment, 25 mg of cannabidiol drop were administered orally daily for 8 weeks. Intervention 2: Control group: In addition to standard treatment, 25 mg placebo drop were administered orally for 8 weeks. Yes - There is a plan to make this available What will be shared: All data will be available. When: Availability will be immediately after the publication of the article. To whom: The data will be available to everyone. Conditions: All required analyzes can be performed and there will be no special conditions for access. Where to obtain: For correspondence send Email to Dr. Majidi/ Mahnaz.majidi@yahoo.com How to obtain: It will reach the applicant in the shortest possible time. Comments:
public Mahnaz Majidi
22 Bahman Hospital, Parstar Alley, Rah-ahan street
Qazvin Iran (Islamic Republic of) 34199-15315 +98 28 3369 9022 Mahnaz.majidi@yahoo.com Qazvin University of Medical Sciences scientific Mahnaz Majidi
22 Bahman Hospital, Parstar Alley, Rah-ahan street
Qazvin Iran (Islamic Republic of) 34199-15315 +98 28 3369 9022 Mahnaz.majidi@yahoo.com Qazvin University of Medical Sciences Iran (Islamic Republic of) Being healthy Obssesive compulsive disorder (OCD) diagnosis through DSM-5 criteria ( DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS, 5TH EDITION) Achieving at least score 16 according to YALE BROWN OBSSESIVE COMPLUSIVE SCORE ( YBOS) Being only on SSRIs through recent 4 weeks Do not have history of using cannabis or other ilicit drugs 18 years 55 years Both Unwilling to participate in this study Having history of other psychiatric disorder including psychotic, cognitive and substance use disorder Being medically ill that cause more side effects than usual Pregnancy, expecting to being pregnant and lactation Achieving score more than 17 through completing Beck Depression scale before starting study F42 Obsessive-compulsive disorder Treatment - Drugs Treatment - Drugs Intervention group: In addition to standard treatment, 25 mg of cannabidiol drop were administered orally daily for 8 weeks. Control group: In addition to standard treatment, 25 mg placebo drop were administered orally for 8 weeks. Intensity of obsessive-compulsive disorder. Timepoint: Before entering into study, in week 4 and 8. Method of measurement: Yale–Brown Obsessive Compulsive Scale. Qazvin University of Medical Sciences Approved 2021-02-27 Ethics committee of Qazvin University of Medical Sciences Deputy of research and technology, Vali-asr street Qazvin Qazvin Iran (Islamic Republic of)