]>
IRCT20210312050680N1 IRCT 2021-03-17 Sabzevar University of Medical Sciences Effect of Tretinoin in treatment of Acnea with Microneeding Comparison of Microneedling Effect with Topical Tretinoin in Treatment of Acne Scars in dermatology clinic 2021-04-04 anticipated 80 Complete https://irct.ir/trial/54976 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Block randomization method was used for randomization. The randomization unit is individual. The allocation of samples in the study was based on random sequence of statistical software (Random allocation software). The sequence used was in the form of four blocks. To hide from the method of opaque envelopes stamped and The wax was applied in a random sequence, Blinding description: All patients divided in 2 groups one of them is control and another group is intervention. A checklist is assigned to each patient After completing the data plan, it is delivered to the statistical consultant who has been blinded. 3 acnea. Intervention 1: The intervention group: after determining the severity of atrophic scars, a dermatologist will undergo microneedling. First, a local anesthetic is injected and given a 30-minute opportunity, in which the Mars device will be used at a speed of 2800 Up to 3200 depending on the location of the scars, the duration of microneedling will vary. In the intervention group, microneedling will be performed in three stages. At 6,12,18 weeks, the amount of improvement is first scored and changes are recorded with a camera. Intervention 2: Control group: In this group, as in the patient intervention group, a dermatologist visits and the severity of the acne scar is determined based on analogous scoring. 2800 to 3200 and depending on the location of the lesions, the time varies, then they come back 6, 12, 18 weeks later, during this period, they use topical retinoid cream every other night. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no more information
public Mohammad Tajik
Bahar St. Medical Dormitory
Sabzevar Iran (Islamic Republic of) 1234567890 +98 51 4487 6532 dr.moh.tajik@gmail.com Sabzevar University of Medical Sciences scientific Maryam karabi
No 80 .Asad Abadi st
Sabzevar Iran (Islamic Republic of) 1234567890 +98 51 4490 8064 maricori@gmail.com Sabzevar University of Medical Sciences Iran (Islamic Republic of) All patients with Acnea Scars in dermatology Clinic 18 years no limit Both Pregnant women. People taking immunosuppressive drugs. People with coagulation failure L90.8 Other atrophic disorders of skin Treatment - Devices Treatment - Drugs The intervention group: after determining the severity of atrophic scars, a dermatologist will undergo microneedling. First, a local anesthetic is injected and given a 30-minute opportunity, in which the Mars device will be used at a speed of 2800 Up to 3200 depending on the location of the scars, the duration of microneedling will vary. In the intervention group, microneedling will be performed in three stages. At 6,12,18 weeks, the amount of improvement is first scored and changes are recorded with a camera Control group: In this group, as in the patient intervention group, a dermatologist visits and the severity of the acne scar is determined based on analogous scoring. 2800 to 3200 and depending on the location of the lesions, the time varies, then they come back 6, 12, 18 weeks later, during this period, they use topical retinoid cream every other night. People with atrophic acne scars who have a theoretical analog scoring system with a score of at least 3. Timepoint: Will be checked in weeks 6, 12 and 18. Method of measurement: Visual Analogue Scale. Vice Chancellor for Research, Sabzevar University of Medical Sciences Approved 2021-03-10 Ethics committee of Sabzevar University of Medical Sciences Asad abadi Sabzevar Razavi Khorasan Iran (Islamic Republic of)