<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20180226038870N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2021-03-05</date_registration>
      <primary_sponsor>Shahid Beheshti University of Medical Sciences</primary_sponsor>
      <public_title>Evaluation of the effectiveness of pulmonary rehabilitation and exercise therapy in reducing the length of hospital stay of patients with Covid-19</public_title>
      <acronym></acronym>
      <scientific_title>Evaluation of the effectiveness of pulmonary rehabilitation and exercise therapy in reducing the length of hospital stay of patients with Covid-19</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2021-05-10</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>100</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/54725</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment.</study_design>
      <phase>N/A</phase>
      <hc_freetext>Covid -19.</hc_freetext>
      <i_freetext>Intervention 1: Intervention group: pulmonary rehabilitation: Daily pulmonary rehabilitation for patients with COVID-19 hospitalized with arterial blood oxygen saturation below 90%, patient will be encouraged to take deep breaths for 30 minutes at heresies. At the same time, the chest muscles will be massaged by a sports medicine specialist. The massage will be done with the palm of the hand, parallel to the ribs and from front to back for 15 minutes. The second movement will be the tapping of the muscles around the chest. This movement will be performed by a sports medicine specialist for 15 minutes while holding the cup in the shape of a hand. This intervention will continue until the patient's arterial blood oxygen saturation reaches above 90%. Intervention 2: Intervention group: Aerobic exercise for patients with 19 patients admitted to hospital with arterial blood oxygen saturation above 90%. Patients will initially be encouraged to walk in the ward for 6 minutes. After they were able to walk this time, we gradually increase the walking time. The rate of increase will be 5 minutes every 2 days.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Yes - There is a plan to make this available</results_IPD_plan>
      <results_IPD_description>What will be shared:
All data is potentially shareable after unidentified individuals

When:
Access starts 6 months after the results are published

To whom:
People working in academic and scientific institutions

Conditions:
The data can be used only with the permission of the author responsible for the study and only for scientific purposes such as sharing in scientific situations. In order to send a request for access to data or documents, it is necessary for the requesting person to send an e.mail to the responsible author and state the purpose of the request for access to data.

Where to obtain:
To receive data and documents related to the project, it is necessary to send an e.mail to the responsible author.
Named: Mehrshad Poursaeed Esfahani 
 e.mail:
mpoorsaid@yahoo.com
Address:
Shahid Chamran Highway, Yemen St., Daneshjoo Blvd., Shahid Taleghani Hospital
And contact number:
982122439948

How to obtain:
After sending the e.mail to the responsible author, within 1-2 weeks, the responsible author will send the appropriate answer to the requesting person.

Comments:
</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Narges Labibzadeh</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Shahid Taleghani hospital, Danshjoo Blv, Velenjak, Shahid Chamran Highway, Tehran,  Iran</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>1985717443</zip>
        <telephone>+98 21 2243 9948</telephone>
        <email>Ddrnlz@gmail.com</email>
        <affiliation>Shahid Beheshti University of Medical Sciences</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Narges Labibzadeh</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Shahid Taleghani hospital, Danshjoo Blv, Velenjak, Shahid Chamran Highway, Tehran,  Iran</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>1985717443</zip>
        <telephone>+98 21 2243 9948</telephone>
        <email>Ddrnlz@gmsil.com</email>
        <affiliation>Shahid Beheshti University of Medical Sciences</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>Pulmonary involvement seen in pulmonary CT spiral consistent with Covid-19 changes diagnosed by a pulmonologist
Positive PCR test for Covid-19 from respiratory or bloody secretions
Normal white blood cell counts with decreased lymphocytes
Drop in arterial blood oxygen saturation below 90% using finger pulse oximetry</inclusion_criteria>
      <agemin>no limit</agemin>
      <agemax>no limit</agemax>
      <gender>Both</gender>
      <exclusion_criteria>The patient does not want to participate in the study or attend another trial.
Patients who are severely ill and need ventilator ventilation.
Patients with musculoskeletal or neurological disorders that prevent the patient from walking normally.</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>J06</hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword>Acute upper respiratory infections of multiple and unspecified sites</hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Treatment - Other</i_code>
      <i_code>Treatment - Other</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention group: pulmonary rehabilitation: Daily pulmonary rehabilitation for patients with COVID-19 hospitalized with arterial blood oxygen saturation below 90%, patient will be encouraged to take deep breaths for 30 minutes at heresies. At the same time, the chest muscles will be massaged by a sports medicine specialist. The massage will be done with the palm of the hand, parallel to the ribs and from front to back for 15 minutes. The second movement will be the tapping of the muscles around the chest. This movement will be performed by a sports medicine specialist for 15 minutes while holding the cup in the shape of a hand. This intervention will continue until the patient's arterial blood oxygen saturation reaches above 90%.</i_keyword>
      <i_keyword>Intervention group: Aerobic exercise for patients with 19 patients admitted to hospital with arterial blood oxygen saturation above 90%. Patients will initially be encouraged to walk in the ward for 6 minutes. After they were able to walk this time, we gradually increase the walking time. The rate of increase will be 5 minutes every 2 days</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Duration of hospitalization. Timepoint: Daily. Method of measurement: Patients' records.</prim_outcome>
      <prim_outcome>Fever. Timepoint: Daily. Method of measurement: Oral thermometer.</prim_outcome>
      <prim_outcome>Patient walking distance. Timepoint: Daily. Method of measurement: Meter.</prim_outcome>
      <prim_outcome>Age. Timepoint: Initial of trial. Method of measurement: Birth certificate.</prim_outcome>
      <prim_outcome>Shortness of breath. Timepoint: Daily. Method of measurement: Respiratory rate.</prim_outcome>
      <prim_outcome>Arterial blood oxygen saturation. Timepoint: Daily. Method of measurement: Digital pulse oxymetery.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome></sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Shahid Beheshti University of Medical Sciences</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2021-02-14</approval_date>
        <contact_name>Ethics committee of Shahid Beheshti University of Medical Sciences</contact_name>
        <contact_address>Taleghani Hospital, Danshjoo Blv, Velenjak, Shahid Chamran Highway, Tehran,  Iran Tehran Tehran Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
