IRCT20180802040665N1 IRCT 2021-02-20 Shahid Beheshti University of Medical Sciences Evaluation of vancomycin pharmacokinetics in patients with augmented renal clearance Evaluation of vancomycin pharmacokinetics with two different regimens in patients with augmented renal clearance 2021-04-04 anticipated 56 Complete https://irct.ir/trial/54210 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Block randomization method was used in this study. 14 blocks including 4 patients generated with online website. In each block, two patients will be assigned to group A (every 12 hours) and two patients will be assigned to group B (every 8 hours). 2-3 Augmented renal clearance. Intervention 1: Intervention group: patients will be received intravenous vancomycin manufactured by Exir pharmaceutical company at dose of 15 to 20 mg/kg every 12 hours. The infusion rate of vancomycin is 1000 mg per hour. Intervention 2: Intervention group: patients will be received intravenous vancomycin manufactured by Exir pharmaceutical company at dose of 15 to 20 mg/kg every 8 hours. The infusion rate of vancomycin is 1000 mg per hour. Yes - There is a plan to make this available What will be shared: All potential data can be shared after blinding When: Six mounts after results published To whom: Researchers working in academic institutions Conditions: For research purposes and meta analysis Where to obtain: Dr. Zahra Sahraei Valieasr St, Niyayesh Highway, Shahid Beheshti University of Medical Sciences, School of Pharmacy, 3rd floor, Department of Clinical Pharmacy Zip Code: 1996835113 Telephone: +982188200209 Email: z.sahraei@sbmu.ac.ir How to obtain: Official letter to the researchers, then after 7 days, their request will be answered. Comments: