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IRCT20210206050270N1 IRCT 2021-07-21 Vice Chancellor for Research, Isfahan University of Medical Sciences Comparison of suction blister and micro punch grafting methods in the treatment of patients with stable vitiligo Comparison of suction blister and micro punch grafting methods in the treatment of patients with stable vitiligo 2020-10-01 anticipated 31 Complete https://irct.ir/trial/54166 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: In each patient, 2 vitiligo patches are selected in similar parts of the body or in symmetrical parts of the body. Then one of the patches is called A and the other B is called by the third person not involved in the study without the patient and the reader. The patch for each intervention will be selected using the online software Random.org so that the two letters A and B are entered in the software, then the letter that the software shows in the first row will indicate the patch that The suction blister on it and the second letter displayed will indicate the patch on which the micro punch grafting will be performed. N/A Vitiligo. Intervention 1: Intervention group: Punch graft 1) Sterilize the graft site 2) The site will be anesthetized with topical lidocaine.3) Harvesting 100-200 2 mm punches in one or more stages 4) Graft implantation with 1.5 punch at the lesion site 5) Dressing the graft site with Vaseline gas 6) Remove the dressing a week later. Intervention 2: Intervention group: suction blister 1) Blisters on healthy areas of the skin that cover areas of the body2) Sterilize the graft site3) The site will be anesthetized with topical lidocaine.4) A vesicle is then formed at the donor site using the device described by Gupta et al.5) At this stage, the vitiligo patch is prepared and the dermis is removed on it by a dermabrator at an average speed of 15,000 rpm until the bleeding spots related to the papillary dermis appear. The blister created is then placed on a glass slide separated by special scissors and carefully placed on the patch.6) The lesion is then bandaged.7) Remove the dressing a week later. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information
public Atefe Samimi
No.186, Farhang Complex, 6th Ave, Shafagh Blv,
Esfahan Iran (Islamic Republic of) 685311654 +98 31 3782 0132 atsamimi71@gmail.com Esfahan University of Medical Sciences scientific Atefe Samimi
No.186, Farhang Complex, 6th Ave, Shafagh Blv,
Esfahan Iran (Islamic Republic of) 8565121654 +98 31 3782 0132 atsamimi71@gmail.com Esfahan University of Medical Sciences Iran (Islamic Republic of) Patients with persistent vitiligo are resistant to medical treatment, ie they have not had a new lesion in the past year and their previous lesions have not become larger. Patients should be between 13 and 65 years old Patients must give informed consent Patients should be willing to cooperate during the study and follow-up period. 13 years 65 years Both Patients with immunodeficiency atients with bleeding disorders Patients being treated for other illnesses L80 Vitiligo Treatment - Devices Treatment - Devices Intervention group: Punch graft 1) Sterilize the graft site 2) The site will be anesthetized with topical lidocaine.3) Harvesting 100-200 2 mm punches in one or more stages 4) Graft implantation with 1.5 punch at the lesion site 5) Dressing the graft site with Vaseline gas 6) Remove the dressing a week later Intervention group: suction blister 1) Blisters on healthy areas of the skin that cover areas of the body2) Sterilize the graft site3) The site will be anesthetized with topical lidocaine.4) A vesicle is then formed at the donor site using the device described by Gupta et al.5) At this stage, the vitiligo patch is prepared and the dermis is removed on it by a dermabrator at an average speed of 15,000 rpm until the bleeding spots related to the papillary dermis appear. The blister created is then placed on a glass slide separated by special scissors and carefully placed on the patch.6) The lesion is then bandaged.7) Remove the dressing a week later Having Complaints. Timepoint: 2 and 4 months after treatment. Method of measurement: questionnaire- visual analog scale (VAS). Improvement Score. Timepoint: 2 and 4 months after treatment. Method of measurement: questionnaire-visual analog scale (VAS). Satisfaction Score. Timepoint: 2 and 4 months after treatment. Method of measurement: questionnaire -visual analog scale (VAS). Esfahan University of Medical Sciences Vice Chancellor for Research, Isfahan University of Medical Sciences Esfahan University of Medical Sciences Approved 2020-10-03 Ethics committee of Isfahan University of Medical Sciences No. 186, Farhang Complex, 6th Ave., Farhang Blvd. Isfahan Isfehan Iran (Islamic Republic of)