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IRCT20210204050238N1 IRCT 2021-03-02 Tehran University of Medical Sciences The effect of zinc supplementation on COVID-19 The effect of zinc supplementation on inflammatory responses and total blood cells counts of patients who infected with COVID-19 2021-03-21 anticipated 44 Complete https://irct.ir/trial/54136 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Supportive, Randomization description: Each person is assigned a code and this code is entered into Excel software, randomization will be done using rand function of Excel software, Blinding description: Physicians and ward nurses are blind about the study group. Patient is blind about the study group. investigator is blind about the study group. data analyzer is blind about the study group. Assignment of patients in treatment and placebo groups is performed by a nurse out of above mentioned groups. N/A COVID-19. Intervention 1: Intervention group: Includes 22 patients with COVID-19 who, in addition to their usual treatments, will take 3*30 mg zinc capsules daily for 2 weeks (14 days) after meals. Intervention 2: Control group: Includes 22 patients with COVID-19 who, in addition to their usual treatments, will take 3 placebo capsules (maltodextrin) daily for 2 weeks (14 days) after meals. Placebo capsules are exactly the same in appearance, color, smell and shape as zinc capsules. Yes - There is a plan to make this available What will be shared: All information can be shared two months after the results are published. When: Two months after the results are published. To whom: Doctors, nurses, and infectious disease specialists Conditions: To evaluate other complementary therapies and compare their effects with existing COVID-19 therapy Where to obtain: Send email to mortezakhamoushi@gmail.com How to obtain: Two months publishing results, send a clear written request by sending an email to mortezakhamoushi@gmail.com. In this case, and finally within one month after receiving the email, the request will be answered. Comments:
public ُُSeyed Morteza Seyed khamoushi
School of Nutritional Sciences & Dietetics, Tehran University of Medical Sciences, No: 44 Hojjat-dost Alley, Naderi St., Keshavarz Blvd, Tehran, Iran
Tehran Iran (Islamic Republic of) 3439123900 +98 21 8895 5975 mortezakhamoushi@gmail.com Tehran University of Medical Sciences scientific Dr. Hossein Imani
School of Nutritional Sciences & Dietetics, Tehran University of Medical Sciences, No: 44 Hojjat-dost Alley, Naderi St., Keshavarz Blvd, Tehran, Iran
Tehran Iran (Islamic Republic of) 3439123900 +98 21 8895 5975 h-imani@sina.tums.ac.ir Tehran University of Medical Sciences Iran (Islamic Republic of) Being 20 to 60 years old Detection of COVID-19 based on PCR test and ward admission Willingness to participate in the study Intravenous daily intake of 8 mg dexamethasone 20 years 60 years Both Taking antibiotics and vitamin D. Advanced Respiratory Distress Syndrome leading to intubation or hospitalization in the intensive care unit History of alcohol and tobacco use U07.1 COVI COVID-19 , virus identified Treatment - Drugs Placebo Intervention group: Includes 22 patients with COVID-19 who, in addition to their usual treatments, will take 3*30 mg zinc capsules daily for 2 weeks (14 days) after meals. Control group: Includes 22 patients with COVID-19 who, in addition to their usual treatments, will take 3 placebo capsules (maltodextrin) daily for 2 weeks (14 days) after meals. Placebo capsules are exactly the same in appearance, color, smell and shape as zinc capsules. Serum C-Reactive Protein level. Timepoint: The first day and the last day of the intervention. Method of measurement: blood analysis. Serum Interleukin-6 level. Timepoint: The first day and the last day of the intervention. Method of measurement: Using blood, serum IL-6 value in Picograms per deciliter by Kit. Blood leukocyte count. Timepoint: The first day and the last day of the intervention. Method of measurement: blood analysis. Total Lymphocyte Count. Timepoint: The first day and the last day of the intervention. Method of measurement: blood analysis. Absolute neutrophil count. Timepoint: The first day and the last day of the intervention. Method of measurement: blood analysis. Tehran University of Medical Sciences Approved 2020-12-05 Vice-Chancellor in Research Affairs- Tehran University of Medical Sciences central headquarters of Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran Tehran Tehran Iran (Islamic Republic of)