IRCT20200825048515N23 IRCT 2021-02-14 Esfahan University of Medical Sciences The effect of topical betamethasone and oral melatonin in the treatment of atopic dermatitis Comparison of the effect of topical betamethasone with oral melatonin in the treatment of atopic dermatitis 2021-02-18 anticipated 50 Complete https://irct.ir/trial/54079 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: In this study, 50 eligible patients will be randomly selected. Then, these patients will be randomly encoded using computer software called "Random Allocation" and automatically divided into two groups. The relevant codes will be entered in the raw checklists and each of these checklists will be randomly assigned to one patient and that patient will be randomly assigned to one of the two study groups, Blinding description: In this study, the two drugs melatonin and placebo of the same color and shape are prepared by the pharmacist and placed in coded packages and given to the doctor. He prescribes them without knowing the type of each drug. Also, the person recording the patient's clinical information and the statistical analyst will not be aware of the type of intervention. 3 Atopic dermatitis. Intervention 1: Control group: In this group, patients receive topical betamethasone and an emollient twice a day. They have also prescribed a placebo tablet (which looks similar to melatonin) at bedtime. Intervention 2: Intervention group: In this group, patients receive topical betamethasone and an emollient twice a day. They have also prescribed an oral melatonin 3 mg tablet at bedtime. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no further information