]>
IRCT20100102002963N31 IRCT 2021-05-02 Azad Islamic University Of Yazd Comparison of the effect of two tranquilizer oral drugs alprazolam and zolpidem on patient,s anxiety before surgery andblood pressure and heart rate before induction of general anesthesia Comparison of the effect of oral administration of alprazolam and zolpidem on patient,s anxiety before surgery and hemodynamic variables before induction of anesthesia 2021-04-21 anticipated 70 Complete https://irct.ir/trial/54078 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: In order to randomly allocate 70 eligible applicants, we randomly divide them into two groups of 35 people. For this purpose, we use Random allocation software version 1.0 under Windows to create a sequence, and by using this software we make A list which is specified from 1 to 70 with group A or B treatment By Using this list, we give the first person who is eligible to enter the study, number one and the last person the number 70, then based on the random allocation list and by the software, it is determined which group A or B each person is in, Blinding description: Patients and researchers themselves are unaware of which medication the patient has received, in this way, each drug is placed in a package and the packages are coded and based on the table of random numbers and specified code, the drug is given to patients by a third party who is not involved in evaluating patients and recording results. 2 The effect of drug type on anxiety before induction of anesthesia. Intervention 1: Patients in the first group are given oral alprazolam (0.5 mg) the night before surgery. Intervention 2: Patients in the second group are given oral zolpidem (5 mg) the night before surgery. Yes - There is a plan to make this available What will be shared: The data obtained from the questionnaires are entered in the statistical software of SPSS version 21 and are statistically analyzed by the relevant statistical tests. The obtained statistical results and its comparison with the results of similar studies are published as a scientific article in one of the prestigious scientific journals. When: Access period starts from 1400 To whom: The statistical results obtained from the statistical analysis of the data of this study will be available to researchers working in academic and scientific institutions. Conditions: Only the results of statistical analysis of the data of this study will be available to university researchers Where to obtain: Dr. Shekoufeh Behdad Professor of Anesthesiology, Shahid Sadoughi University of Medical Sciences, Yazd. Mobile phone number: 09131514144 Email: behdad90@gmail.com How to obtain: The applicant should send his / her application by e-mail or mobile phone and the requested documents will be sent to him / her within a few days. Comments:
public Dr.Shokofe Behdad
Yazd, Bahonar Square, the central building of Yazd University of Medical Sciences
Yazd Iran (Islamic Republic of) 8915887857 +98 35 3822 1386 drbehdad@ssu.ac.ir Yazd University of Medical Sciences scientific Dr.Shokofe Behdad
Yazd, Bahonar Square, the central building of Yazd University of Medical Sciences
Yazd Iran (Islamic Republic of) 8915887857 +98 35 3822 1386 drbehdad@ssu.ac.ir Yazd University of Medical Sciences Iran (Islamic Republic of) Includes all female patients undergoing abdominal surgery for women referred to Shahid Sadoughi Hospital in Yazd 20 years 60 years Female Existence of moderate to severe systemic disease history of using of sedative or tranquilizer drugs history of addiction to opioids or any sedative or psychotropic drugs patient disagreement for cooperation in this study Treatment - Drugs Treatment - Drugs Patients in the first group are given oral alprazolam (0.5 mg) the night before surgery. Patients in the second group are given oral zolpidem (5 mg) the night before surgery. Anxiety score. Timepoint: Before administration of study drug and before induction of anesthesia. Method of measurement: VAS(0-10). Systolic blood pressure. Timepoint: Before administration of study drug and before induction of anesthesia. Method of measurement: Using monitoring device. Diastolic blood pressure. Timepoint: Before administration of study drug and before induction of anesthesia. Method of measurement: Using monitoring device. Mean arterial pressure. Timepoint: Before administration of study drug and before induction of anesthesia. Method of measurement: Using monitoring device. Heart Rate. Timepoint: Before administration of study drug and before induction of anesthesia. Method of measurement: Using monitoring device. Azad Islamic University Of Yazd Approved 2021-03-15 Ethics Committee of Ali Ibn Abi Talib Medical School (AS), Islamic Azad University, Yazd Branch Safaieh, Boulevard of the Shohadaie Gomnam YAZD Yazd Iran (Islamic Republic of)