]>
IRCT20201214049707N1 IRCT 2021-04-19 Sanandaj University of Medical Sciences the best concentration of injected hypertonic dextrose in knee prolotherapy Evaluation of the effect of different concentrations of dextrose in prolotherapy on relieving knee osteoarthritis pain 2021-05-05 anticipated 93 Complete https://irct.ir/trial/53806 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: We use blocked randomisation method. In this method we choose nine paper that writed on three of them H, three M and three L. We mix this nine papers and take one of them for every patient randomly and categories them acording to their paper, Blinding description: In time of procedure, patient and performer are blind about patient's category and individual that receive and write afect of procedure is blind too. 2-3 Knee Osteoarthritis. Intervention 1: Intervention group: first group : 16 millilitres of Dextrose 15 % plus 4 millilitres of lidocaine 2 %, inject in four points in the anterior and four points in the posterior of knee. This will be repeat two times with distance of two weeks. Intervention 2: Intervention group: Second group :16 millilitres of Dextrose 30% plus 4 millilitres of lidocaine 2 %, inject in four points in the anterior and four points in the posterior of knee. This will be repeat two times with distance of two weeks. Intervention 3: Intervention group: Third group 16 millilitres of Dextrose 50 % plus 4 millilitres of lidocaine 2 %, inject in four points in the anterior and four points in the posterior of knee. This will be repeat two times with distance of two weeks. Yes - There is a plan to make this available What will be shared: The major information of patient's chronic disease, risk factors and kind of the intervention are capable for publication after doing unrecognisable patient's identity When: One to three months after presentation and print the consequences in origin university To whom: All researchers and Co_workers in medical field Conditions: Use of this research and deployment that is possible for researchers and those who have speciality and licence in medical field. Where to obtain: Dsbiglary@gmail.com No: 00989183715979 How to obtain: Applying for above addresses and presentation documents for authentication and obligation for taking necessary and legal licenses Comments:
public Saeid Biglary
No.4,Khane Aftab,Tahmasebi street, Shark Saadi , phase 2, Sanandaj
Sanandaj Iran (Islamic Republic of) 6617953775 +98 87 3362 8194 Saeid.Biglary@muk.ac.ir Sanandaj University of Medical Sciences scientific Saeid Biglary
No.4,Khane Aftab,Tahmasebi street, Shark Saadi , phase 2, Sanandaj
Sanandaj Iran (Islamic Republic of) 6617953775 +98 87 3362 8194 Saeid.Biglary@muk.ac.ir Sanandaj University of Medical Sciences Iran (Islamic Republic of) At least three of this six criteria Age more than 50 year's Morning stiffness less than 30 minutes Cripitation in knee moves Bone sensivity Bone enlarged No feeling of arther warming 50 years no limit Both Stroid drugs injection in the last two weeks Diabetes mellitus Candidate for knee surgery( degree's of four in stiffness ) History of dextrose injection in knees Knee infection in the last three months Knee inflammation Daily opium use History of inflammatory or infected arthritis Heridatory or traumatic injury in knee joint Vascular necrosis Body mass index more than 30 M17 Osteoarthritis of knee Treatment - Drugs Treatment - Drugs Treatment - Drugs Intervention group: first group : 16 millilitres of Dextrose 15 % plus 4 millilitres of lidocaine 2 %, inject in four points in the anterior and four points in the posterior of knee. This will be repeat two times with distance of two weeks. Intervention group: Second group :16 millilitres of Dextrose 30% plus 4 millilitres of lidocaine 2 %, inject in four points in the anterior and four points in the posterior of knee. This will be repeat two times with distance of two weeks. Intervention group: Third group 16 millilitres of Dextrose 50 % plus 4 millilitres of lidocaine 2 %, inject in four points in the anterior and four points in the posterior of knee. This will be repeat two times with distance of two weeks. Severity of pain is the most important item that is affected on disability of patients with knee osteoarthritis and in this research through the WOMAC score evaluate before and after the procedure. Timepoint: Before intervention, one, three and six months after the first injection. Method of measurement: Via questionnaire that designed for this research plus WOMAC score questionnaire. Severity of the pain is the most important item and the most affected on patient's disability that evaluates. Morning stiffness is a limiter cause that evaluates. Restriction for daily activities will evaluates. Timepoint: Before intervention, one, three and six months after the first injection. Method of measurement: Via WOMAC score questionnaire. Sanandaj University of Medical Sciences Approved 2021-03-17 Ethic committee of kurdistan university of medical sciences No.4,Khane Aftab Building, Tahmasebi street, Shark Saade phase 2, Sanandaj SANANDAJ Kurdistan Iran (Islamic Republic of)