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IRCT20180923041097N5 IRCT 2022-02-01 The University of Sistan and Baluchestan Effect of aerobic exercise and garlic consumption on rheumatoid arthritis The effect of eight weeks of aerobic exercise and garlic supplementation on fatigue and cardiovascular risk factors in women with rheumatoid arthritis 2021-09-11 anticipated 48 Complete https://irct.ir/trial/53518 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Factorial, Purpose: Supportive, Randomization description: Random allocation is done by simple randomization method. First, 3 groups based on the number of participants in each group and the number of groups required for the trial (placebo, exercise, exercise and placebo), are formed and then a 2 digit code is given to each subject without any criteria from 01 to 48. Then a number is selected in the table of random numbers, with the eyes closed, and in the row to the right of the desired number, up to 16 two-digit numbers less than 48 for the first group, 16 second two-digit numbers for the second group and 16 third two-digit numbers for the third group will be considered, Blinding description: In the present trial, there are two groups of exercise, one receiving supplement and the other receiving placebo. The Supervisor is the only one who is aware of the contents of the capsules containing the supplement and placebo, and provides these capsules to the evaluator students for the use of the subjects in the supplement and exercise + supplement groups. Thus, participants, evaluators and statistical analysts do not know which group is a exercise group and which group is a exercise + supplement group. 2 Rheumatoid Arthritis. Intervention 1: First intervention group: This group pedals on the ergometer (Body sculpture brand made in China)for eight weeks, 3 sessions per week, in each session after 10 minutes of warm-up, with an intensity of 70% of the maximum oxygen consumption, and then cools down for 10 minutes and daily receives 2 rounds of placebo (corn starch under the Zamen brand, manufactured by Etminan Hadaf Toos Company, which was prepared in the amount of 500 mg in coatings similar to garlic supplement capsules by the researcher). Intervention 2: Second intervention group: This group pedals on the ergometer for eight weeks, 3 sessions per week and in each session after 10 minutes of warm-up, with an intensity of 70% of the maximum oxygen consumption, and then cools down for 10 minutes. Take 2 times a day garlic supplement with Garcin brand made by Goldaro company, Iran in a dose of 500 mg. Intervention 3: Third intervention group: This group receives 500 mg of garlic supplement(with brand of Garcin produced by Gol daro Company), twice a day for eight weeks. Yes - There is a plan to make this available What will be shared: Subjects' information is shared with other researchers after being Unrecognizable. When: After the publication of the final research report. To whom: Academic researchers Conditions: Citing the findings by citing the source Where to obtain: By email address How to obtain: After receiving the request via email and reviewing the request by the scientific officer of the research, will be answered. Comments:
public Reza Delavar
Department of Sports Sciences, Sistan and Baluchestan University, University Street.
Zahedan Iran (Islamic Republic of) 9816745845 +98 54 3113 2674 delavar@ped.usb.ac.ir The University Sistan and Baluchestan scientific Reza ِDelavar
Department of Sport Sciences, Faculty of Psychology and Educational Sciences, University of Sistan and Baluchestan, , University Blvd.
Zahedan Iran (Islamic Republic of) 9816745845 +98 54 3113 6724 delavar@ped.usb.ac.ir University of Sistan and Baluchestan Iran (Islamic Republic of) Women with rheumatoid arthritis Women with rheumatoid arthritis who are of childbearing age. Women with rheumatoid arthritis aged 27 to 45 years. 27 years 45 years Female Women with rheumatoid arthritis who also have cardiovascular disease. M05.04 Felty's syndrome, hand Behavior Treatment - Other Treatment - Other First intervention group: This group pedals on the ergometer (Body sculpture brand made in China)for eight weeks, 3 sessions per week, in each session after 10 minutes of warm-up, with an intensity of 70% of the maximum oxygen consumption, and then cools down for 10 minutes and daily receives 2 rounds of placebo (corn starch under the Zamen brand, manufactured by Etminan Hadaf Toos Company, which was prepared in the amount of 500 mg in coatings similar to garlic supplement capsules by the researcher). Second intervention group: This group pedals on the ergometer for eight weeks, 3 sessions per week and in each session after 10 minutes of warm-up, with an intensity of 70% of the maximum oxygen consumption, and then cools down for 10 minutes. Take 2 times a day garlic supplement with Garcin brand made by Goldaro company, Iran in a dose of 500 mg. Third intervention group: This group receives 500 mg of garlic supplement(with brand of Garcin produced by Gol daro Company), twice a day for eight weeks. Systolic blood pressure above 14 mm Hg. Timepoint: 24 hours before and 24 hours after the first and last session of the exercise program. Method of measurement: By arm blood pressure monitor. Total cholesterol above 250 mg per deciliter. Timepoint: 24 hours before and 24 hours after the first and last session of the exercise program. Method of measurement: Total cholesterol diagnostic kit made by Pars Azmoun company by photometric method. Blood LDL level above 160 mg per deciliter. Timepoint: 24 hours before and 24 hours after the first and last session of the exercise program. Method of measurement: Low density lipoprotein diagnostic kit made by Pars Azmon Company by photometric method. Fatigue rate above 3 points. Timepoint: 24 hours before and 24 hours after the first and last session of the exercise program. Method of measurement: Fatigue Symptom Inventory questionnaire. The University of Sistan and Baluchestan Approved 2020-06-02 Ethics Committee of Sistan and Baluchestan University. Central Organization of Sistan and Baluchestan University, University Blvd, Zahedan, Iran Zahedan Sistan-va-Balouchestan Iran (Islamic Republic of)