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IRCT20191013045092N2 IRCT 2021-01-01 Shiraz University of Medical Sciences A comparative study on the therapeutic effect of combined NBUVB and systemic Simvastatin with NBUVB alone in patients with vitiligo A comparative study on the therapeutic effect of combined NBUVB (Narrow Band Ultraviolet B) and systemic Simvastatin with NBUVB alone in patients with vitiligo 2015-10-16 anticipated 50 Complete https://irct.ir/trial/53236 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Patients are referred to a secretary to be blindly assigned to one of the two groups A and B based on block randomization. Drugs are provided to patients in sealed paper bags on a monthly basis. 2 times a day for the second month (3 times a day and the third and fourth months 4 times a day) and the second group of patients on placebo (made by Shiraz School of Pharmacy), Blinding description: Informed concent will be taken from the participants and they don't know that they are recieving drug or placebo. the investigator and the care giver don't know the intervention and placebo group. 3 Vitiligo. The first group of simvastatin 20 mg made by Iranian company Poursina (first month 2 times a day in the second month 3 times a day in the third and fourth month 4 times a day) and the placebo group (made by Shiraz School of Pharmacy) similar to the first month of simvastatin twice a day and then 3 times a day The third and fourth months are used 4 times a day. Similar to simvastatin, the first month is used twice a day and then 3 times a day and the third and fourth months 4 times a day.. Yes - There is a plan to make this available What will be shared: Article When: Article publication time To whom: researchers Conditions: In order to raise the scientific level of researchers in this field through articles Where to obtain: The executor of the plan How to obtain: Submit a request, review the executor of the project and send feedback Comments:
public Dr. Ladan Dastgheib
Shiraz, Zand street, Shahid faghihi hospital, floor 3, Dermatology Department
Shiraz Iran (Islamic Republic of) 7134846114 +98 71 3231 9049 dastgh@sums.ac.ir Shiraz University of Medical Sciences scientific Dr. Ladan Dastgheib
Shiraz, Zand street, Shahid faghihi hospital, floor 3, Dermatology Department
Shiraz Iran (Islamic Republic of) 7134846114 +98 71 3231 9049 dastgh@sums.ac.ir Shiraz University of Medical Sciences Iran (Islamic Republic of) Patients who have just started treatment and have not taken medication in the last 6 months 16 years no limit Both Patients with liver and kidney problems Pregnant or breastfeeding Patients taking simvastatin interfering drug Under 16 years old L80 Vitiligo Treatment - Drugs The first group of simvastatin 20 mg made by Iranian company Poursina (first month 2 times a day in the second month 3 times a day in the third and fourth month 4 times a day) and the placebo group (made by Shiraz School of Pharmacy) similar to the first month of simvastatin twice a day and then 3 times a day The third and fourth months are used 4 times a day. Similar to simvastatin, the first month is used twice a day and then 3 times a day and the third and fourth months 4 times a day. Investigation of skin re-pigmentation rate. Timepoint: Months 1, 2, 3 and 4. Method of measurement: Repetition of experiments, photography and scoring. Shiraz University of Medical Sciences Approved 2016-07-01 Ethics comittee of Shiraz University of Medical sciences Shiraz, Zand street, medical university, ethics comittee Shiraz Fars Iran (Islamic Republic of)