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IRCT20171210037809N7 IRCT 2020-12-09 Islamic Azad University Effect of weight training and whey protein on gene expression Atrial natriuretic peptide(ANP), Brain natriuretic peptide (BNP) and galactin 3 Effect of a weight training period and whey protein on gene expression Atrial natriuretic peptide(ANP), Brain natriuretic peptide (BNP) and galactin 3 inactive men 60-65 years old 2020-12-08 anticipated 129 Complete https://irct.ir/trial/52856 interventional Randomization: Not randomized, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Other, Other design features: This study was designed with emphasis on anabolic, structural, adaptive, and cardiac damage effects.Research sample are older men in the age range of 60-65 years who live in certain conditions. In previous studies Used of athletes; young bodybuilders, heart patients and rats.Using free weights (high availability, lower cost than using gyms, not being with young people, etc.) and consuming protein whey may improve and reduce cardiac biomarkers (heart and brain peptides and Galactin 3) .Also use of supplements (protein Whey) with resistance training may cause synergistic physiological effects, Blinding description: None of the subjects know what substance they will consume. N/A We have no disease / The effect of his protein is considered with exercise. Intervention 1: training group: Exercise is a 6-week exercise protocol (3 sessions per week) with an intensity of 60 to 70% of a variable maximum repetition will perform by exercise groups. Intervention 2: training + Whey Protein group: Exercise is a 6-week exercise protocol (3 sessions per week) with an intensity of 60 to 70% of a variable maximum repetition will perform by exercise groups and Individuals will be requested to bring their daily packages containing 35 grams (30 grams of protein or placebo + 5 grams of syrup powder) daily (one hour before and immediately after exercise or in between Morning and evening meal). Intervention 3: Whey Protein:Individuals will be requested to bring their daily packages containing 35 grams (30 grams of protein or placebo + 5 grams of syrup powder) daily (one hour before and immediately after exercise or in between Morning and evening meal). Intervention 4: No training and supplements. No - There is not a plan to make this available Justification or reason for not sharing IPD is No more information
public Siavash Shahdusti
naghshe- jahan
Varamin-Pishva Iran (Islamic Republic of) 33817-74895 +98 21 3672 5011 info@iauvaramin.ac.ir Islamic Azad University scientific Siavash Shahdusti
naghshe-jahan/ IAU
Varamin- Pishva Iran (Islamic Republic of) 33817-74895 021036725011 dastavard96@gmail.com Islamic Azad University Iran (Islamic Republic of) Over the past six months, they have not consumed any supplements or medications It does not exclude any history of common chronic health problems and diseases, such as respiratory, metabolic, cardiovascular, renal and hepatic diseases 60 years 65 years Male Over the past six months, they have not consumed any supplements or medications It does not exclude any history of common chronic health problems and diseases, such as respiratory, metabolic, cardiovascular, renal and hepatic diseases Other Other Other Other training group: Exercise is a 6-week exercise protocol (3 sessions per week) with an intensity of 60 to 70% of a variable maximum repetition will perform by exercise groups. training + Whey Protein group: Exercise is a 6-week exercise protocol (3 sessions per week) with an intensity of 60 to 70% of a variable maximum repetition will perform by exercise groups and Individuals will be requested to bring their daily packages containing 35 grams (30 grams of protein or placebo + 5 grams of syrup powder) daily (one hour before and immediately after exercise or in between Morning and evening meal) Whey Protein:Individuals will be requested to bring their daily packages containing 35 grams (30 grams of protein or placebo + 5 grams of syrup powder) daily (one hour before and immediately after exercise or in between Morning and evening meal) No training and supplements Atrial natriuretic peptide(ANP). Timepoint: At the beginning of the study (before the intervention) and after 6 weeks of supplementation and exercise. Method of measurement: Blood collection :changes Atrial natriuretic peptide (ANP): pg /ml. Brain natriuretic peptide(BNP). Timepoint: At the beginning of the study (before the intervention) and after 6 weeks of supplementation and exercise. Method of measurement: Blood collection :changes Atrial natriuretic peptide(BNP) : pg /ml. Galectin3. Timepoint: At the beginning of the study (before the intervention) and after 6 weeks. Method of measurement: Blood collection :changes Galectin 3 : pmo /ml. Islamic Azad University Approved 2020-04-21 Ethics Committee of the Faculty of Medical Sciences of Islamic Azad University, Varamin Prison naghshe- jahan/ IAU VARAMIN varamin/ pishva Tehran Iran (Islamic Republic of)