IRCT20150721023282N15 IRCT 2021-03-01 Esfahan University of Medical Sciences The effect of garlic on fatigue and quality of life in MS patients Evaluation of the garlic extract (Allium sativum) effect to improving fatigue and quality of life in patients with multiple sclerosis (MS) a randomized, placebo-controlled clinical trial 2020-11-29 anticipated 56 Complete https://irct.ir/trial/52817 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Supportive, Randomization description: Block randomization method using blocks of size 4 will be used. So that all possible sequences of two drug and two placebo in each block will be made with each block being numbered. Then, using random number table, the blocks will be selected randomly and the patients will be assigned to the two groups of drug and placebo according to the the blocks sequences, Blinding description: Patients, the prescribing physician and the data analyst will be blind to the intervention type. The drug and placebo will be prepared in similar coded bottles and given to the chief researcher. A bottle will be given to each patient according to the chief researcher. 3 Multiple Sclerosis. Intervention 1: Intervention group: Allium 400-mg tablets (manufactured by Amin company), every 12 hours, for 4 weeks. Intervention 2: Placebo group: Placebo tablets (manufactured by Amin company), every 12 hours, for 4 weeks. No - There is not a plan to make this available Justification or reason for not sharing IPD is Confidentiality of patients data