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IRCT20201124049481N1 IRCT 2021-08-12 Shahid Beheshti University of Medical Sciences Comparison of the effect of high protein diet in people at risk of premature menopause Comparison of the effect of three high animal protein diet , high plant protein and common protein on indicators related to ovarian aging (premature menopause) in people at risk of premature ovarian failure: a clinical trial 2021-09-23 anticipated 90 Complete https://irct.ir/trial/52562 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Other, Purpose: Prevention, Randomization description: Sampling will be done in a stratified manner using random permutation blocks. For this purpose, first individuals are classified based on body mass index and then for each category using random block method of individuals in two groups of intervention and a control Will be appointed. The randomization unit is individual. Statistical software is used for randomization. N/A Premature menopause. Intervention 1: Group 1: Animal high protein diet. Intervention 2: Intervention group: Intervention group: high protein plant diet. Yes - There is a plan to make this available What will be shared: ======== When: Up to two months after the end of the intervention To whom: Professors and students in the field of nutrition Conditions: or more extensive research on this disease Where to obtain: To Shahid Beheshti School of Nutrition, Dr. Mirmiran How to obtain: Must be approved by the supervisor Dr. Mirmiran Comments:
public Marjan bedakhanian
No. 7, Hafezi St., Shahid Farahzadi Blvd., Ghods Town (West), Tehran, Iran Institute of Nutrition and Food Industry Research
Tehran Iran (Islamic Republic of) 1981619573 0000000 marjanbadakhanian@ymail.com Shahid Beheshti University of Medical Sciences scientific Marjan bedakhanian
No. 7, Hafezi St., Shahid Farahzadi Blvd., Ghods Town (West), Tehran, Iran Institute of Nutrition and Food Industry Research
Tehran Iran (Islamic Republic of) 1981619573 00000000 marjanbadakhanian@ymail.com Shahid Beheshti University of Medical Sciences Iran (Islamic Republic of) Women in their 20s and 40s who have stopped menstruating or two to three periods a year and have Anti Mullerian hormone level as defined in the scientific definitions and FSH level above 10 IU / L. are at risk for premature menopause Normal creatine or GFR levels above 70 No change in supplements (antioxidants) Informed consent to participate in the study 20 years 40 years Female Having a history of radiotherapy Having a history of ovarian surgery E28.31 Premature menopause Lifestyle Lifestyle Group 1: Animal high protein diet Intervention group: Intervention group: high protein plant diet Serum level of Anti Mullerian Hormone. Timepoint: It will be measured at the beginning and end of the study. Method of measurement: It will be measured by ELISA method. Premature menopause. Timepoint: Not applicable. Method of measurement: Based on the AMH level according to the table mentioned in the. Serum level of Estrogen. Timepoint: At the beginning and 6 months after starting the diet. Method of measurement: It will be measured by ELISA method. Serum level of Progestron. Timepoint: At the beginning and 6 months after starting the diet. Method of measurement: It will be measured by ELISA method. Serum level of Follicle-stimulating hormone (FSH). Timepoint: At the beginning and 6 months after starting the diet. Method of measurement: It will be measured by ELISA method. Serum level of Luteinizing Hormone (LH). Timepoint: At the beginning and 6 months after starting the diet. Method of measurement: It will be measured by ELISA method. Serum level of Inhibin A. Timepoint: At the beginning and 6 months after starting the diet. Method of measurement: It will be measured by ELISA method. Serum level of Inhibin B. Timepoint: At the beginning and 6 months after starting the diet. Method of measurement: It will be measured by ELISA method. Serum level of C-Reactive Protein. Timepoint: At the beginning and 6 months after starting the diet. Method of measurement: It will be measured by ELISA method. Sonography. Timepoint: At the beginning and end of the study in terms of ovarian volume, number of antral follicles, antral thickness. Method of measurement: Ultrasound device. Shahid Beheshti University of Medical Sciences Approved 2021-05-12 Institute of Nutrition and Food Industry No. 7, Shahid Hafezi St. (West Purple), Shahid Farahzadi Blvd. Tehran Tehran Iran (Islamic Republic of)