IRCT20200929048878N1 IRCT 2020-11-18 Iranian academic center for education culture and research Comparison of the effect of combined herbal medicine with routine medicine on sperm quality and chromatine integrity in oligoasthenoteratozoospermia men The study of the effect of combination herbal therapy (zayesh booalidaroo®+ Safoof hefz + Royal gel) on sperm quality and chromatine integrity in oligoasthenoteratozoospermia men 2020-10-22 anticipated 50 Complete https://irct.ir/trial/51284 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: The way to select groups is that they will be assigned to groups based on block randomization. Blocks of size 4 are considered. So we will have six blocks containing AABB, ABAB, BBAA, BABA, ABBA, BAAB. Each block will also be randomly selected using a dice throw. For example, if thrown dice is 3, the BBAA block is considered, and therefore the first two patients are assigned to treatment B and the next two patients to treatment A. The dice will be thrown 20 times to complete the assignment of patients to the treatment groups. randomization is performed using the DOE option in MINITAB ver 15 software. 3 Oligoasthenotratosospermia. Intervention 1: Intervention group: group of Zayesh Majoon(Twice a day, 8 grams each time), Royal Jelly capsule and Safof hefz capsule (made by BooaliDaroo company) Twice a day for a 90-day period. Intervention 2: Control group: Sprigen oral supplement (contains vitamins C, E, D3, B1, B2, B6, B12, A, folic acid, Zinc, niacin, biotin, magnesium, L-carnitine, coenzyme Q10, inositol and N-acetylcysteine) and tamoxifen (2 tablets in the morning and evening) over a period of 90 days. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Undecided - It is not yet known if there will be a plan to make this available