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IRCT20200913048697N1 IRCT 2020-09-28 Yazd University of Medical Sciences Effect of vitamin d on inflammatory factors The effect of vitamin D injection on tumor necrosis factor alpha (TNF) and vascular cell adhesion molecule 1 (SVCAM-1) in vitamin D deficient patients with Type 2 Diabeties 2020-08-22 anticipated 50 Complete https://irct.ir/trial/50994 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Randomization description: The 50 patients included in the study will be divided into intervention group with monthly vitamin D injection (25 subjects) and control group (25 subjects) using simple randomization and SPSS statistical software. Individuals will be randomly assigned to intervention and control groups, Blinding description: For concealment after randomization by the random allocation table, we select and number the envelope sample size and then write the control and intervention group identification sheets based on the output of the table and then provide the sealed envelope for drug or control allocation for medical staff. 1-2 Diabetic patients with vitamin D deficiency.. Intervention 1: Intervention group: Doses of 200,000 international units of vitamin D were injected at the beginning and one month after the start of the study, a total of 400,000 international units. Intervention 2: Control group: The control group does not receive anything. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information.
public Siavash Babaie
No. 5,. Northern 1,. Eastern 2,. Alley 4 Amir kabir Blvd, Kerman.
Kerman Iran (Islamic Republic of) 7618874714 +98 34 3211 8778 S.babaie86@gmail.com Yazd University of Medical Sciences scientific Siavash Babaie
No. 3, Second Eastern, First Northern, Forth Alley, Amir kabir Blvd, Kerman.
Kerman Iran (Islamic Republic of) 7618874714 +98 34 3211 8778 S.babaie86@gmail.com Yazd University of Medical Sciences Iran (Islamic Republic of) Having diabetes and HbA1c less than 9 percent 25-hydroxy vitamin d serum level less than 20 ng per milliliter Aged 30-60 30 years 60 years Both Lack of interest in participating in the study Vitamin d supplement intake in last 3 month Impaired absorption, liver and kidney diseases and severe infection Immune system suppressor medication Pregnancy and lactation Insulin using E08 Diabetes mellitus due to underlying condition Prevention Prevention Intervention group: Doses of 200,000 international units of vitamin D were injected at the beginning and one month after the start of the study, a total of 400,000 international units. Control group: The control group does not receive anything. Tumor necrosis factor alpha. Timepoint: before intervention, 2 month after intervention. Method of measurement: Using laboratory kits for measuring the desired factors with ELISA technique. Soluble vascular cell adhesion molecule 1. Timepoint: before intervention, 2 month after intervention. Method of measurement: Using laboratory kits for measuring the desired factors with ELISA technique. Yazd university of Medical Science Approved 2020-05-16 Ethics Committee in Research School of Health - Shahid Sadoughi University of Medical Sciences, Yazd Yazd, Alam Square, Shohadaye Gomnam Boulevard, Medical Sciences Campus, Faculty of Health Yazd Yazd Iran (Islamic Republic of)