]>
IRCT20200816048427N1 IRCT 2020-10-15 Ahvaz University of Medical Sciences Comparison of the Efficacy of Metformin and Inofolic in Ovulation Comparison of the Efficacy of Metformin and Inofolic in Ovulation induction in Patients with resistant Polycystic Ovarian Syndrome 2018-04-21 anticipated 40 Complete https://irct.ir/trial/50368 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Simple individual randomization method, numbering of all samples starting from 01 to 40, then first 20 people selected using random numbers table are allocated to intervention A and the rest to intervention B. The researcher must first preset the direction for reading the table numbers (for example, up, down, left or right) then the researcher touches one of the numbers and moves in one of the predefined directions and records the numbers. And assigns to group A. The rest are assigned to Group B. 2 polycystic ovarian syndrome(PCOS). Intervention 1: First Intervention group: group of metformin (receiving 1 tablet of 500 mg twice daily). Intervention 2: Second Intervention group: group of inofolic (receiving 1 sochet twice a day, half an hour before breakfast and half an hour before dinner ). No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no more information
public Razieh Ghanbarzadeh
Ekhlas 6 Ave, Jahadgaran Alley
Dorud Iran (Islamic Republic of) ۶۸۸۱۷۹۴۶۷۱ +98 61 3624 1035 12azie.gh@gmail.com Ahvaz University of Medical Sciences scientific Razieh Ghanbarzadeh
Ekhlas 6 Ave, Jahadgaran Alley
Dorud Iran (Islamic Republic of) ۶۸۸۱۷۹۴۶۷۱ +98 61 3624 1035 12azie.gh@gmail.com Ahvaz University of Medical Sciences Iran (Islamic Republic of) Presence of Oligomenorrhoea Presence of Amenorrhea Presence of Polycysticovarian Evidence in Ultrasound Hypergonadism Lack of Response to Ovulation Induction Therapy 22 years 32 years Female Lack of patient cooperation Inability to follow treatment for 3 months. E28.2 Polycystic ovarian syndrome Treatment - Drugs Treatment - Drugs First Intervention group: group of metformin (receiving 1 tablet of 500 mg twice daily) Second Intervention group: group of inofolic (receiving 1 sochet twice a day, half an hour before breakfast and half an hour before dinner ) Follicular growth. Timepoint: The size of the follicles at the beginning of treatment (before the intervention) and 90 days after the start of metformin and inofolic. Method of measurement: transvaginal ultrasonography. Number of dominant follicles. Timepoint: At the beginning of the study (before the intervention) and 90 days after the start of metformin and inofolic. Method of measurement: transvaginal ultrasonography. Ahvaz Jundishapur University of Medical Sciences Approved 2018-11-17 Ethics committee of Ahvaz Jondishapur University of Medical Sciences Ekhlas 6 Ave, Jahadgaran Alley Dorud Lorestan Iran (Islamic Republic of)