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IRCT20180630040290N4 IRCT 2020-08-06 Tabriz University of Medical Sciences Effect of coenzyme Q10 supplement on chronic gingivitis inflammation in diabetic patients The effect of supplementation of Q10 coenzyme with Scaling and root planing (SRP) on periodontal and gingival indexes in controled diabetic patients 2020-07-25 anticipated 42 Complete https://irct.ir/trial/49867 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Sampling method is randomly available among individuals referring to periodontics department of Tabriz dental faculty. The randomization method is simple and the unit is individual, our tool for randomization is the randomized number chart. Furthermore, the allocation of traetment to patients is done randomly. To do this, the types of the traetment are identified with code A (Q10 coenzyme with Scaling and root planing (SRP)) and B (SPR) and then the traetment are sealed in envelopes that will be placed in a box and stirred. Then they are randomly chosen from the box and after observing the code, the traetment is given to the patient. None of the patients will be informed about another patient's traetment. The a evaluater will olso be is not informed about type of traetment, Blinding description: The present study is one-way blind and the a evaluater will olso be is not informed about type of traetment. N/A Controlled diabetes. Intervention 1: Intervention group:Coenzyme Q10 will be administered with SRP for 30 days, after which periodontal and gingival index values ​​will be measured. Patients were randomly divided into two groups and will given 200 mg of coenzyme Q10 or placebo daily for 30 days. For all patients, coenzyme Q10 prescription and oral hygiene training and accurate SRP will performe by a therapist in a one-hour session. For this purpose, hand tools, ultrasonic and rubber cap and pumice paste will be used. Intervention 2: Control group: The SRP will be prescribed for 30 days and then relating to periodontal and jinjal indicators will be measured. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information
public Amir reza Babaloo
Dentistry faculty, Tabriz University of Medical Sciences, Golgasht
Tabriz Iran (Islamic Republic of) 5166614711 +98 41 3335 5921 amirezababaloo@yahoo.com Tabriz University of Medical Sciences scientific Amir reza Babaloo
Dentistry faculty, Tabriz University of Medical Sciences, Golgasht
Tabriz Iran (Islamic Republic of) 5166614711 +98 41 3335 5921 amirezababaloo@yahoo.com Tabriz University of Medical Sciences Iran (Islamic Republic of) Diabetic patients referred to the periodontitis Department of Tabriz Dental School Having informed consent Having age 29 to 59 29 years 59 years Both People with systemic disease Pregnant women E10.6 Type 1 diabetes mellitus with other specified complications Treatment - Drugs Treatment - Devices Intervention group:Coenzyme Q10 will be administered with SRP for 30 days, after which periodontal and gingival index values ​​will be measured. Patients were randomly divided into two groups and will given 200 mg of coenzyme Q10 or placebo daily for 30 days. For all patients, coenzyme Q10 prescription and oral hygiene training and accurate SRP will performe by a therapist in a one-hour session. For this purpose, hand tools, ultrasonic and rubber cap and pumice paste will be used. Control group: The SRP will be prescribed for 30 days and then relating to periodontal and jinjal indicators will be measured Pocket Depth. Timepoint: Before the intervention , one months after initiating the intervention. Method of measurement: A periodontal probe is used to measure this parameter. The first sign visible at the top of the envelope is the depth of the envelope. Clinical Attachment Level. Timepoint: Before the intervention , one months after initiating the intervention. Method of measurement: The clinical adhesion of the gums is obtained by the difference between the distance from the gingival margin to the plaque floor from the CEJ distance to the gingival margin. Plaque index. Timepoint: Before the intervention , one months after initiating the intervention. Method of measurement: Plaque index is obtained from dividing the number of levels with plaque on the total number of multiplication levels in 100 . Bleeding index. Timepoint: Before the intervention , one months after initiating the intervention. Method of measurement: Bleeding index (BI) is measured using the University of North Carolina probe_15 (UNC-15) probe. Tabriz University of Medical Sciences Approved 2020-07-20 Ethics Committee of Tabriz University of Medical Sciences Central office of Tabriz University of Medical Sciences, Golgasht Ave, Azadi Blvd Tabriz East Azarbaijan Iran (Islamic Republic of)