]>
IRCT20200722048167N1 IRCT 2020-08-08 Islamic Azad University Effect of aerobic training and omega-3 exercise on oxidative and inflammatory elements in obese women Effects of aerobic training and omega-3 supplementation on the levels of Paraoxonase, myeloperoxidase and some inflammatory and oxidative markers in overweight and obese women’s 2020-05-04 anticipated 40 Complete https://irct.ir/trial/49833 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Factorial, Purpose: Prevention, Randomization description: Using the lottery method, the names of the subjects on a piece of paper It is written separately and placed inside a container then the names of the subjects are removed and is placed in the intervention group or placebo. The first 30 names are placed in the intervention group and the rest in the placebo group, Blinding description: Placebo and supplement Omega 3 are placed inside the similar capsules. Patients and researchers are not aware of the type of supplement received. 3 Overweight and obesity. Intervention 1: Intervention group: Omega 3 supplement group (taking omega 3 supplement, not participating in aerobic exercise program):for 8 weeks and daily 2000 mg of omega 3 fatty acid supplement in the form of two 1000 mg capsules containing 360 mg of Eicosa pentanoic acid and 240 mg of Docosa hexaenoic acid (morning and night) made by Karen)and do the activities of daily living. Intervention 2: Intervention group: Aerobic training group (participation in aerobic training program- not taking omega3 supplements):The training program including 8 weeks of aerobic training(Running or fast walking) every week 3 sessions. Intensity of training in the first two weeks 50 to 55%, in the second two weeks 55 to 60%, in the third two weeks 60 to 65% and in the fourth two weeks 65 to 70% maximum heart rate is designed and the duration of each exercise session is about 25 It is minutes. Before and after each exercise session, 10 minutes of warm-up and eight minutes of cooling are performed, respectively.During this week, take placebo capsules morning and night. (Similar to omega-3 capsules but containing oral paraffin).Made by Darogster Company. Intervention 3: Intervention group: Aerobic training group + omega 3 supplement (taking omega 3 supplement and simultaneously participating in aerobic training program ): for 8 weeks and daily 2000 mg of omega 3 fatty acid supplement in the form of two 1000 mg capsules containing 360 mg of Eicosa pentanoic acid and 240 mg of Docosa hexaenoic acid (morning and night) made by Karen) in addition to the training program including 8 weeks of aerobic training (Running or fast walking)every week 3 sessions. Intensity of training in the first two weeks 50 to 55%, in the second two weeks 55 to 60%, in the third two weeks 60 to 65% and in the fourth two weeks 65 to 70% maximum heart rate is designed and the duration of each exercise session is about 25 It is minutes. Before and after each exercise session, 10 minutes of warm-up and eight minutes of cooling are performed, respectively. Intervention 4: Control group: Placebo group (not participating in aerobic exercise program, not taking omega 3 supplements) During these 8 weeks, take placebo capsules morning and night. (Similar to omega-3 capsules but containing oral paraffin) Made by Darogster Company,In addition to daily life activities. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no more information
public Shila Montazer
North Alley 2 West 2، Elahieh Street،Nasr Boulevard
Kerman Iran (Islamic Republic of) 7618698181 +98 34 3245 3916 shilamontazer@gmail.com Islamic Azad University scientific Mohammad Ali Azarbayjani
Shohada of Hesarak Boulevard,University Square,Shahid Sattari Highway
Tehran Iran (Islamic Republic of) 1477893855 +98 21 4486 9827 M_Azarbayjani@iauctb.ac.ir Islamic Azad University Iran (Islamic Republic of) Age range 25 to 40 years; Physical health; Subjects' body mass index more than 25 kg / m2 and less than 35 kg / m2; Ability to participate in aerobic exercise program; Not participating in regular exercise for the past year; No diagnosed diseases such as diabetes, cardiovascular, cancer, gastrointestinal diseases, liver, kidney, autoimmune diseases, inflammation, thyroid, polycystic ovary syndrome; Do not take antihypertensive drugs or lipid-lowering drugs; Do not take nutritional supplements for at least six months before the study. 25 years 40 years Female No signing informed consent Smoking or drinking alcohol at least once a week Use of contraceptives and nonsteroidal anti-inflammatory drugs (NSAIDs) in the last 3 months Pregnancy and lactation E66.0 Obesity due to excess calories Prevention Prevention Prevention Placebo Intervention group: Omega 3 supplement group (taking omega 3 supplement, not participating in aerobic exercise program):for 8 weeks and daily 2000 mg of omega 3 fatty acid supplement in the form of two 1000 mg capsules containing 360 mg of Eicosa pentanoic acid and 240 mg of Docosa hexaenoic acid (morning and night) made by Karen)and do the activities of daily living Intervention group: Aerobic training group (participation in aerobic training program- not taking omega3 supplements):The training program including 8 weeks of aerobic training(Running or fast walking) every week 3 sessions. Intensity of training in the first two weeks 50 to 55%, in the second two weeks 55 to 60%, in the third two weeks 60 to 65% and in the fourth two weeks 65 to 70% maximum heart rate is designed and the duration of each exercise session is about 25 It is minutes. Before and after each exercise session, 10 minutes of warm-up and eight minutes of cooling are performed, respectively.During this week, take placebo capsules morning and night. (Similar to omega-3 capsules but containing oral paraffin).Made by Darogster Company Intervention group: Aerobic training group + omega 3 supplement (taking omega 3 supplement and simultaneously participating in aerobic training program ): for 8 weeks and daily 2000 mg of omega 3 fatty acid supplement in the form of two 1000 mg capsules containing 360 mg of Eicosa pentanoic acid and 240 mg of Docosa hexaenoic acid (morning and night) made by Karen) in addition to the training program including 8 weeks of aerobic training (Running or fast walking)every week 3 sessions. Intensity of training in the first two weeks 50 to 55%, in the second two weeks 55 to 60%, in the third two weeks 60 to 65% and in the fourth two weeks 65 to 70% maximum heart rate is designed and the duration of each exercise session is about 25 It is minutes. Before and after each exercise session, 10 minutes of warm-up and eight minutes of cooling are performed, respectively. Control group: Placebo group (not participating in aerobic exercise program, not taking omega 3 supplements) During these 8 weeks, take placebo capsules morning and night. (Similar to omega-3 capsules but containing oral paraffin) Made by Darogster Company,In addition to daily life activities. Paraoxonase 1. Timepoint: First, the end of the study. Method of measurement: ELISA Kit. Myeloperoxidase. Timepoint: First, the end of the study. Method of measurement: ELISA Kit. Apolipoprotein A1. Timepoint: First, the end of the study. Method of measurement: ELISA Kit. Apolipoprotein B. Timepoint: First, the end of the study. Method of measurement: ELISA Kit. C-Reactive Protein. Timepoint: First, the end of the study. Method of measurement: Bionic Kit. Blood Suger. Timepoint: First, the end of the study. Method of measurement: Glucose Test Kit. Insulin. Timepoint: First, the end of the study. Method of measurement: Insulin ELISA Kit. VO2 max. Timepoint: First, the end of the study. Method of measurement: Rockport test and formula method. Body Mass Index. Timepoint: First, the end of the study. Method of measurement: Twice the height / weight. Vice Chancellor for Research, Faculty of Literature, Tehran University of Research Sciences Approved 2020-06-24 Ethics Committee of Islamic Azad University - University Scientific Unit Tehran - End of Shahid Sattari Highway - University Square - Hesarak Martyrs Boulevard Kerman Kerman Iran (Islamic Republic of)