IRCT20190407043194N2 IRCT 2020-07-22 Mashhad University of Medical Sciences Evaluation the effect of propolis on rheumatoid arthritis Determining the Effect of Propolis Supplementation on Inflammatory Factors and Oxidative Status in Women with Rheumatoid Arthritis 2021-08-06 anticipated 48 Complete https://irct.ir/trial/49430 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Supportive, Randomization description: Participants will allocate in each group by: Allocation will randomize in blocks of size 4 (two placebos,two propolis) will design by RAS software. Each block will stratify by patient's baseline characteristics of body mass index (less or more than 30 kg/m²), Severity of disease (moderate or sever) and menstrual status (yes or no), Blinding description: In this study investigator and participants are blind from groups and how they are randomized. 3 Arthritis rheumatoid. Intervention 1: Intervention group: Propolis supplement (Propolis supplement capsule containing 500 mg of propolis, Shahdineh Golha Pharmaceutical Company, 2 times a day, daily consumption for 3 months, with water). Intervention 2: Control group: Placebo (placebo capsule containing 500 mg of wheat starch, Shahdineh Golha Pharmaceutical Company, 2 times a day, daily consumption for 3 months, with water). Yes - There is a plan to make this available What will be shared: Primary outcomes will be share. When: Starting 6 month after publication To whom: Researchers Conditions: For Metanalysis Where to obtain: Making contact with Dr. Mariam Khosravi How to obtain: Making contact with Dr. Mariam Khosravi and asking for the data, if she approved, request will be send to university president, if they approved the data will send for applicant. Comments: