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IRCT20180503039517N4 IRCT 2020-07-14 Islamic Azad University The effects of beta-hydroxy beta-methyl butyrate HMB supplementation with selected resistance training on Liver, Muscular, Kidney Enzymes, Lipid Profile, Body Combination, Strength and Some Other Physical Fitness Factors in Bodybuilding Athletes The effects of beta-hydroxy beta-methyl butyrate HMB supplementation with selected resistance training on some biochemical factors of blood and strength in bodybuilding athletes 2019-05-05 anticipated 63 Complete https://irct.ir/trial/49189 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Other, Randomization description: 40 bodybuilders were selected by available sampling method. Through drawing (The participants' names were written on paper and selected through a simple random draw for the two intervention groups and a control group), Blinding description: In this research, participants are unaware of the group assigned to themselves and other participants. A separate workout hour is considered for each intervention group. The person in charge of collecting data and the processor are also unaware of the type of intervention and the people involved in the research groups. N/A supplementation in body builders. Intervention 1: The experimental group performed selected resistance exercises for 8 weeks and 3 sessions per week and received HMB supplement in the amount of 3 g per day as two suckers for 14 days. Blood samples are taken from all samples in the laboratory before and after exercise (48 hours apart) and some biochemical factors such as liver, muscle, kidney, and lipid profiles are analyzed in the serum of the subjects. Placed. Intervention 2: Control group: The selected resistance exercises were performed for 8 weeks and 3 sessions per week and the polydextrose capsule was taken in the amount of 3 g per day as two suckers for 14 days. Blood samples are taken from all samples in the laboratory before and after exercise (48 hours apart) and some biochemical factors such as liver, muscle, kidney, and lipid profiles are analyzed in the serum of the subjects. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no further information
public Soleyman Ansari Kolachahi
second floor, Adibsaber Apartment, next to Esparo restaurant, Prof. Samei Blv.
RASHT Iran (Islamic Republic of) 4193193933 +98 911 230 6198 solomonansari@yahoo.com Islamic Azad University scientific Soleyman Ansari Kolachahi
second floor, Adibsaber Apartment, next to Esparo restaurant, Prof. Samei Blv.
RASHT Iran (Islamic Republic of) 4193193933 +98 911 230 6198 solomonansari@yahoo.com Islamic Azad University Iran (Islamic Republic of) Age (19-29years) Gender (male) a maximum of 3 months involving in resistance exercise 19 years 29 years Male smoking having cardiorespiratory, musculoskeletal, neurological, hormonal or orthopedic disorders No ingestion of androgenic and energetic supplements in the past 1 months Other Placebo The experimental group performed selected resistance exercises for 8 weeks and 3 sessions per week and received HMB supplement in the amount of 3 g per day as two suckers for 14 days. Blood samples are taken from all samples in the laboratory before and after exercise (48 hours apart) and some biochemical factors such as liver, muscle, kidney, and lipid profiles are analyzed in the serum of the subjects. Placed. Control group: The selected resistance exercises were performed for 8 weeks and 3 sessions per week and the polydextrose capsule was taken in the amount of 3 g per day as two suckers for 14 days. Blood samples are taken from all samples in the laboratory before and after exercise (48 hours apart) and some biochemical factors such as liver, muscle, kidney, and lipid profiles are analyzed in the serum of the subjects. Serum levels of liver enzymes (Aspartate transaminase (AST) and Alanine transaminase (ALT). Timepoint: Initial blood sampling will be performed in the pre-test phase two days before the start of the study, and final blood sampling will be performed in the post-test phase two days after the end of the study in the laboratory. Method of measurement: Using the Pars Azmoun laboratory kit (made in Iran) according to the manufacturer's instructions and the ELISA method. Serum levels of muscle enzymes (Creatine kinase (CK) and lactate dehydrogenase (LDH)). Timepoint: Initial blood sampling will be performed in the pre-test phase two days before the start of the study, and final blood sampling will be performed in the post-test phase two days after the end of the study in the laboratory. Method of measurement: Using Pars Azmoun laboratory kit (made in Iran) according to the manufacturer's instructions and the ELISA method. Serum levels of renal function enzymes (the blood urea nitrogen (BUN), Creatinine and Urea. Timepoint: Initial blood sampling will be performed in the pre-test phase two days before the start of the study, and final blood sampling will be performed in the post-test phase two days after the end of the study in the laboratory. Method of measurement: Using the Pars Azmoun laboratory kit (made in Iran) according to the manufacturer's instructions and the ELISA method. Serum levels of Lipid profile (low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, Total cholesterol and triglycerides. Timepoint: Initial blood sampling will be performed in the pre-test phase two days before the start of the study, and final blood sampling will be performed in the post-test phase two days after the end of the study in the laboratory. Method of measurement: Using Biosystems Laboratory kit (made in Spain), according to the manufacturer's instructions and the ELISA method. Some physical fitness factors (strength, body composition and power). Timepoint: Initial measurements in the pre-test phase will be performed two days before the start of the study, and final measurement in the post-test phase will be performed two days after the end of the study at the club. Method of measurement: One maximum repetition test and body mass index (BMI) will be used to measure strength and body composition. Islamic Azad University of Rasht Branch Approved 2020-04-29 The ethics committee of Islamic Azad University, Rasht Branch Islamic Azad University, Rasht Branch, Lakan Blv RASHT Guilan Iran (Islamic Republic of)