]>
IRCT20200607047680N1 IRCT 2020-06-18 Tabriz University of Medical Sciences anesthetic effect of Perilocain versus Mepivacain in inferior alveolar nerve block Comparision of success rate of inferior alveolar nerve block protocol in mandibular first molars with symptomatic irriversible pulpitis by Prilocain and Mepivacain local anaesthesia: A randomized control clinical trial 2020-01-21 anticipated 100 Complete https://irct.ir/trial/48730 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: In this study randomization performed by Datinf Randlist software using a simple random sampling method, Blinding description: In this double-blinded study, both patients and researchers were unaware of group stratification. Patients were kept blind about the fact that in which group they enrolled. Also, all used anesthetic agents were unlabeled and coded by a third party before use. 3 Inferior alveolar nerve block. Intervention 1: Intervention group: Inferior alveolar nerve block performed by single-shot injection of 2 cartridges of 3% mepivacaine (manufactured by Inibsa Dental s.t.u co) using a standard syringe with 27G, 3.6 cm needle. Intervention 2: Intervention group: Intervention group: Inferior alveolar nerve block performed by single-shot injection of 2 cartridges of 3% prilocaine_felypressin 0/03IU (manufactured by DarouPakhsh Pharmaceutical MFG co) using a standard syringe with 27G, 3.6 cm needle. Yes - There is a plan to make this available What will be shared: Individual participant data that underlie the reported results after proper deidentification When: following publication under the policy of the publisher To whom: Researchers who provide a methodologically sound proposal Conditions: to achieve aims in the approved proposal Where to obtain: Requests should be proposed to Dr. M. Eskandarinezhad via sending an email to eskandarinezhadmahsa@yahoo.com. How to obtain: proposals should be directed to "eskandarinezhadmahsa@yahoo.com". To gain access data requestors will need to sign a data access agreement. Comments:
public Mahsa Eskandarinezhad
Endodontics department, faculty of dentistry, Daneshgah Ave.
Tabriz Iran (Islamic Republic of) 5166614711 +98 41 3335 5965 Eskandarinezhadmahsa@yahoo.com Tabriz University of Medical Sciences scientific Mahsa Eskandarinezhad
Endodontics department, faculty of dentistry, Daneshgah Ave.
Tabriz Iran (Islamic Republic of) 5166614711 +98 41 3335 5965 Eskandarinezhadmahsa@yahoo.com Tabriz University of Medical Sciences Iran (Islamic Republic of) Patients between 18 and 65 years Indication of Root Canal Treatment (RCT) on firs molar tooth Normal periapical appearance Patient's consent to participate in the study Evidence of symptomatic irreversible pulpitis that shows a predominant pain in response to cold pulp sensibility test compared to the control teeth 18 years 65 years Both History of allergy to anesthetic agents (of any kind) Use of painkillers within 6 hours prior to the procedure Use of any kind of medication with possible interaction with anesthetic agents Presence of any pathological lesions at the site of injection Previous history of facial trauma Presence of pathological pocket while probing Patients without response to cold pulp sensibility test Presence of periradicular pathology severe than PDL widening Patients with partial necrosis Treatment - Drugs Treatment - Drugs Intervention group: Inferior alveolar nerve block performed by single-shot injection of 2 cartridges of 3% mepivacaine (manufactured by Inibsa Dental s.t.u co) using a standard syringe with 27G, 3.6 cm needle. Intervention group: Intervention group: Inferior alveolar nerve block performed by single-shot injection of 2 cartridges of 3% prilocaine_felypressin 0/03IU (manufactured by DarouPakhsh Pharmaceutical MFG co) using a standard syringe with 27G, 3.6 cm needle. Level of analgesia based on Visual Analog Scale. Timepoint: 15 minutes after injection. Method of measurement: Visual Analog Scale. Tabriz University of Medical Sciences Approved 2020-01-20 Research Ethics committee of Tabriz University of Medical Science Ethics committee office,Tabriz University of Medical Science, Golgasht Ave., Azadi Blv. Tabriz East Azarbaijan Iran (Islamic Republic of)