<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20200608047685N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2020-06-30</date_registration>
      <primary_sponsor>Mashhad University of Medical Sciences</primary_sponsor>
      <public_title>Investigating the effect of acupressure on postpartum hemorrhage</public_title>
      <acronym></acronym>
      <scientific_title>The effect of pressure on Gallbladder points on Postpartum Hemorrhage after vaginal delivery</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2020-07-22</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>70</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/48711</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Randomization description: simple.In this method, a table of random numbers is used for randomization. In this way, in order to read random numbers in the mentioned table, from top to bottom, the even numbers are considered for the intervention group and the individual numbers are considered for the control group.</study_design>
      <phase>3</phase>
      <hc_freetext>post partum hemorrhage.</hc_freetext>
      <i_freetext>Intervention 1: Intervention group: In the third stage of labor, immediately after removal of the fetus and simultaneous infusion of 20 IU oxytocin, according to national guideline natural childbirth, in groups of 60 seconds on each of the cranial gallbladder (GB8-GB16-GB17-GB18) (collectively 4 minutes) apply. After the expulsion of the placenta and the completion of the third stage of labor, every 15 minutes to an hour (4 cycles) and then every 30 minutes to an hour (two cycles) one cycle of pressure on parts of the above apply (7 cycles Pressure: 28 min pressure ) (distances pressure on the precise location of the control points of the fourth stage of labor, vaginal delivery, according to national guideline, is.Immediately after the placenta is removed, the plastic bags of blood collected by the researcher are placed under the mother's buttocks, and after 2 hours, the blood in these bags is weighed. Intervention 2: Control group: In the control group, normal care of the fourth stage of labor (including injection of 20 units of intravenous oxytocin and uterine massage at intervals of 15 minutes in the first hour after delivery and every 30 minutes in the second hour of delivery), as well as the intervention group at the stated intervals. Immediately after the placenta is removed, the plastic blood collection bags are placed under the mother's buttocks by the researcher, and after 2 hours, the blood in these bags is weighed.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Undecided - It is not yet known if there will be a plan to make this available</results_IPD_plan>
      <results_IPD_description>Justification or reason for indecision in sharing IPD is There is no more information.</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Mansouri</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Ebnesina st,DoctoraCrossroad</address>
        <city>Mashhad</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>13944-91388</zip>
        <telephone>+98 51 3273 5002</telephone>
        <email>mansourie94150@mums.ac.ir</email>
        <affiliation>Mashhad University of Medical Sciences</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>mansouri</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Ebnesina st,DoctoraCrossroad</address>
        <city>Mashhad</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>13944-91388</zip>
        <telephone>+98 51 3273 5002</telephone>
        <email>mansourie94150@mums.ac.ir</email>
        <affiliation>Mashhad University of Medical Sciences</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>Single pregnancy
Healthy and alive fetus
Admission for vaginal delivery
Pregnancy age 42-37 weeks
Vertex position
Lack of internal disease and surgery
Absence of any scar or wound on the acupressure point
No history of cesarean section or previous uterine surgery
Body mass index less than 30
Absence of high-risk pregnancy (gestational diabetes, pregnancy hypertension ...)
Fourth and less pregnancy</inclusion_criteria>
      <agemin>18 years</agemin>
      <agemax>45 years</agemax>
      <gender>Female</gender>
      <exclusion_criteria>Childbirth with vacuum and forceps
Rupture of the uterus or cervix
Accelerated Liber (less than 3 hours)
Use relaxing medications such as magnesium sulfate or halogenated anesthesia
Severe bleeding before the intervention
Grade 3 and 4 tears
Macrosomia (fetal weight greater than 4.5 kg)
Severe arterial bleeding from the tear or episiotomy
Manual removal of placenta and membranes
Requires additional rutin treatments such as metrogen, misoprostrol</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>o72.1</hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword></hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Prevention</i_code>
      <i_code>N/A</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention group: In the third stage of labor, immediately after removal of the fetus and simultaneous infusion of 20 IU oxytocin, according to national guideline natural childbirth, in groups of 60 seconds on each of the cranial gallbladder (GB8-GB16-GB17-GB18) (collectively 4 minutes) apply. After the expulsion of the placenta and the completion of the third stage of labor, every 15 minutes to an hour (4 cycles) and then every 30 minutes to an hour (two cycles) one cycle of pressure on parts of the above apply (7 cycles Pressure: 28 min pressure ) (distances pressure on the precise location of the control points of the fourth stage of labor, vaginal delivery, according to national guideline, is.Immediately after the placenta is removed, the plastic bags of blood collected by the researcher are placed under the mother's buttocks, and after 2 hours, the blood in these bags is weighed.</i_keyword>
      <i_keyword>Control group: In the control group, normal care of the fourth stage of labor (including injection of 20 units of intravenous oxytocin and uterine massage at intervals of 15 minutes in the first hour after delivery and every 30 minutes in the second hour of delivery), as well as the intervention group at the stated intervals. Immediately after the placenta is removed, the plastic blood collection bags are placed under the mother's buttocks by the researcher, and after 2 hours, the blood in these bags is weighed.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Postpartum hemorrhage. Timepoint: 2 hours after delivery, placentas and membranes. Method of measurement: Plastic bags collect blood.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome></sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Mashhad University of Medical Sciences</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2020-04-28</approval_date>
        <contact_name>Ethics Committee of Mashhad University of Medical Sciences</contact_name>
        <contact_address>Ebnesina Ave,Doktora Cross Mashhad Razavi Khorasan Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
