<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20200531047612N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2020-07-08</date_registration>
      <primary_sponsor>Islamic Azad University</primary_sponsor>
      <public_title>Effect of eight weeks of water resistance training and consumption of dark chocolate on serum myostatin Amounts, balance and appetite of the elderly</public_title>
      <acronym>ندارد</acronym>
      <scientific_title>The effect of 8 weeks WATER RESISTANCE EXERCISE with DARK CHOCOLATE  SUPPLEMENTATION on serum MYOSTATIN level,  Balance and Appetite in older adults</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2019-10-17</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>40</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/48530</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Basic scienece, Randomization description: Simple - using a table of random numbers - so that by giving people from 0 to 40 the first number we find in the first intervention group: the practice group is placed, the second number in the second intervention group: the complementary group + practice, The third number in the third intervention group: the complementary group and the fourth number in the fourth intervention group , the control group.</study_design>
      <phase>N/A</phase>
      <hc_freetext>Water resistance training - the elderly.</hc_freetext>
      <i_freetext>Intervention 1: Intervention group: Exercise group: The subjects of this group performed water resistance training for eight weeks (three sessions per week, one session per hour). Intervention 2: Intervention group: Exercise + supplement group: The subjects of this group performed water resistance training for eight weeks (three sessions per week, one session per hour) and in these eight weeks 30 grams of dark chocolate daily (6 bitter chocolates 83% , 5 g) received. Intervention 3: Intervention group: Supplementary group: The subjects of this group did not have any sports activities and for eight weeks they received only 30 grams of dark chocolate daily (6 bitter chocolates 83%, 5 g) received. Intervention 4: Intervention group: Control group: The subjects of this group did not have any sports activities and supplementation during this period of eight weeks And they went on with their normal lives.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Undecided - It is not yet known if there will be a plan to make this available</results_IPD_plan>
      <results_IPD_description>Justification or reason for indecision in sharing IPD is There is no further information</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>maryam mousavi</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Tehran - End of Shahid Sattari Highway - University Square - Shohadae Hesarak Blvd. - Islamic Azad University, Science and Research Branch .</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>: ۱۴۷۷۸۹۳۸۵۵</zip>
        <telephone>+98 21 4432 9092</telephone>
        <email>Mousavi6082068@gmail.com</email>
        <affiliation>Islamic Azad University</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Dr. Farshad Ghazalian</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Tehran - End of Shahid Sattari Highway - University Square - Shohadae Hesarak Blvd. - Islamic Azad University, Science and Research Branch .</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>۱۴۷۷۸۹۳۸۵۵</zip>
        <telephone>+98 21 4486 8495</telephone>
        <email>phdghazalian@gmail.com</email>
        <affiliation>Islamic Azad University</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>Healthy seniors were between the ages of 60 and older and sedentary (not participating in regular sports activities for the past 12 months).
60 - 73
Inactivity (not participating in regular sports activities in the last 12 months)</inclusion_criteria>
      <agemin>60 years</agemin>
      <agemax>73 years</agemax>
      <gender>Female</gender>
      <exclusion_criteria>Specific diseases such as chronic lung disease
Ischemic heart disease
Heart valve disease
Blood pressure disease
Harmful fats
Hypertrophic heart disease
smoking
Do not take supplements or medications for the past month
Mental illness (such as dementia)
Muscle and joint injuries (such as lumbar disc protrusion)</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code></hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword></hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Other</i_code>
      <i_code>Other</i_code>
      <i_code>Other</i_code>
      <i_code>Other</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention group: Exercise group: The subjects of this group performed water resistance training for eight weeks (three sessions per week, one session per hour).</i_keyword>
      <i_keyword>Intervention group: Exercise + supplement group: The subjects of this group performed water resistance training for eight weeks (three sessions per week, one session per hour) and in these eight weeks 30 grams of dark chocolate daily (6 bitter chocolates 83% , 5 g) received.</i_keyword>
      <i_keyword>Intervention group: Supplementary group: The subjects of this group did not have any sports activities and for eight weeks they received only 30 grams of dark chocolate daily (6 bitter chocolates 83%, 5 g) received.</i_keyword>
      <i_keyword>Intervention group: Control group: The subjects of this group did not have any sports activities and supplementation during this period of eight weeks And they went on with their normal lives.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Myostatin. Timepoint: Before the intervention, after eight weeks of intervention. Method of measurement: Blood sample by ELISA by special kit.</prim_outcome>
      <prim_outcome>The balance. Timepoint: Before the intervention, after eight weeks of intervention. Method of measurement: Perform spot stain testing.</prim_outcome>
      <prim_outcome>Appetite. Timepoint: Before the intervention, after eight weeks of intervention. Method of measurement: Questionnaire for mood swings.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome>Water resistance training. Timepoint: Before the intervention, after eight weeks of intervention. Method of measurement: Based on the level of understanding the effort (PRE) is measured.</sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>research fellow</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2019-10-16</approval_date>
        <contact_name>Islamic Azad University- Sience and Research Branch</contact_name>
        <contact_address>Tehran - End of Shahid Sattari Highway - University Square - Shohadae Hesarak Blvd. - Islamic Azad University, Science and Research Branch . Tehran Tehran Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
