IRCT20190415043279N4 IRCT 2020-06-14 Sanandaj University of Medical Sciences Effect of local application of Glycyrrhiza glabra and eucalyptus extract for the prevention of Mucositis Effect of local application of Glycyrrhiza glabra and eucalyptus extract for the prevention of chemoradiation Induced Oral Mucositis in head and neckmalignancies 2019-06-22 anticipated 60 Complete https://irct.ir/trial/48507 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: In this research, according to a randomized list, is assigned by a person outside the study according to the corresponding codes in the sealed envelopes, then assigned to any disease that is included in the study. Medications are identical in appearance, packaging, color, and so on, Blinding description: Container solutions and placebo were identical with respect to appearance and only differed in coding of the capsules. The treatment code of the intervention supplements was blinded for subjects, investigators and staff involved in the conduct of the study. 3 Oral Mucositis. Intervention 1: Intervention group: The recipient of the solution containing Glycyrrhiza glabra and eucalyptus extract, It is recommended to use 20 cc of it as a gargle for 30 seconds three times a day. Intervention until the end of the course of radiochemotherapy, the solution is prepared by a phytochemical specialist in a specialized laboratory. Intervention 2: Control group: The recipient of the container containing the normal saline solution, It is recommended to use 20 cc as a gargle for 30 seconds. Intervention until the end of the course of radiochemotherapy, the solution is prepared by a phytochemical specialist in a specialized laboratory. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information