IRCT20200112046095N1 IRCT 2020-05-30 Zahedan University of Medical Sciences The effect of tranexamic acid on reduction of edema and ecchymosis Investigation the effect of tranexamic acid on reduction of edema and ecchymosis in patients undergoing rhinoplasty 2020-03-20 anticipated 120 Complete https://irct.ir/trial/48453 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: Block randomization with blocks of 10. The patients will be randomly assigned into 2 groups of 60. Considering the sample size of 120 ( 60 patients in tranexamic acid group and 60 patients in placebo group) , 12 blocks with 10 people will be selected; in each block there will be 5 cards of each group. So by selecting each block, 5 people will be assigned into each group, Blinding description: Tranexamic acid drugs and placebo boxes have a similar appearance so the patients are blinded ( When giving a written consent, it will be explained to the patients that for improving the accuracy of the results, the patients should be blinded but they are either in tranexamic acid or placebo group. The cons and pros of each treatment option will be explained). Assignment of the patients into two groups will be done by the student (researcher) and the surgeon who will also evaluate the patients after surgery for the edema and ecchymosis won't be aware of the assignment so he is blinded. 2-3 Rhinoplasty. Intervention 1: Intervention group: Receiving 1000 mg tranexamic acid 2 hours before operation and 1000 mg every 8 hours after operation for 3 times. Intervention 2: Control group: Receiving tranexamic acid placebo 2 hours before operation and every 8 hours after operation for 3 times. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information.