IRCT20140804018677N4 IRCT 2020-06-03 Shahid Beheshti University of Medical Sciences Reepaven effect on severity of pain and bleeding during menstruation Investigation of the effect of Reepaven drug on severity of pain and bleeding during menstruation in women of childbearing age compared with placebo 2019-01-21 anticipated 80 Complete https://irct.ir/trial/48332 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: In this study, patients were assigned to two groups of Reepaven and placebo based on a Simple randomization method. This means that all participants had an equal chance of being in each group. The first step is to create a random sequence. For this purpose, we used a table of random numbers. From the beginning, it was decided to go down to read the numbers in the table of random numbers, after selecting the starting point. We then determined that even numbers were assigned to the intervention group and individual numbers were assigned to the placebo group. Due to the fact that when using simple randomization methods, especially in low sample size, it is possible that the two groups do not equal at the same time, so if a group reaches its sample size earlier, then we must ignore the relevant figures, and complete the opposite group. One of the project's colleagues put his finger on a point in the table with his eyes closed, and then, as scheduled, moved down and wrote down the numbers until they reached the sample size in both groups. Each number, depending on whether they were even or odd, represented a group to which we assigned code A (intervention) and B (placebo). With this method, we had a specific sequence of 80 codes A and B at the end, indicating that the first to eightieth person to be included in the study should belong to each group. We wrote the code on a piece of paper in order and put it in an envelope, to use it during sampling. Thus, after reviewing the entry criteria and, if the client wishes, we entered each person into the groups according to our pre-determined list. 3 Women with painful menstrual cramps or heavy bleeding. Intervention 1: Intervention group: Reepaven from Ghaem Darou Company (Persicaria bistorta, Quercus, Saccharum spontaneum and Punica granatum); in the first two days of menstruation, 3 pills a day (after breakfast, lunch and dinner) and on the remaining days of the period, 2 pills daily (after lunch and dinner). Intervention 2: Control group: placebo; in the first two days of menstruation, 3 pills a day (after breakfast, lunch and dinner) and on the remaining days of the period, 2 pills daily (after lunch and dinner). Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information.