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IRCT20200505047310N1 IRCT 2020-06-10 Ardabil University of Medical Sciences Evaluation of the sedative effect of thyme in cough in children with asthma Evaluation of sedative effect of thyme on cough in children 5 to 12 years of age with asthma 2020-08-22 anticipated 60 Complete https://irct.ir/trial/48032 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization method is a simple randomizing using a table of random numbers, a set of numbers which is completely generated randomly without any specific pattern or order in a table form. Table numbers are read from the left, in a way that even numbers are assigned to intervention A and odd numbers to intervention B. In this way, the researcher touches one of the numbers and moves to the right, then records the numbers and assigns them to different groups. Next, considering the volume of the research sample, aluminum wrapper envelopes are prepared (in order not to clarify the content of the envelopes), each of the random sequences is recorded on a card and placed inside an envelope. To maintain a random sequence, envelopes are numbered in the same way. Finally, the flap of the envelopes are sealed and respectively placed inside a box. To reveal the participants' assigned group, at the beginning of the registration based on the order of eligible participants entry to study, one of the envelopes is opened, Blinding description: Due to the fact that placebo is used, patients and outcome assessors are unaware of the type of intervention. 2 Asthma. Intervention 1: Intervention group: Patients in the intervention group will be given 1 to 4 grams of dried thyme leaf powder prepared as a syrup for a week, at a dose of 20 mg / kg every 8 hours, along prednisolone tablets (1 mg / kg, daily, Abureyhan Co.), salbutamol spray (2 puffs every 3 hours by Caspian Tamin Co), theophylline syrup (4 cc every 6 hours by Elixir Co) with routine medical treatment. Intervention 2: Control group: Control group will receive 2 cc placebo syrup and prednisolone tablets (1 mg / kg, daily, Abureyhan Co.), salbutamol spray (2 puffs every 3 hours by Caspian Tamin Co), theophylline syrup (4 cc every 6 hours by Elixir Co) with routine medical treatment. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Study results are not clear yet.
public Elnaz Eskandar pour
Moallem Street
Ardabil Iran (Islamic Republic of) 5615783134 +98 45 3325 2251 e.eskandarpour@arums.ac.ir Ardabil University of Medical Sciences scientific Elnaz Eskandar pour
Moallem Street
Ardabil Iran (Islamic Republic of) ۵۶۱۳۶۴۳۱۹۷ +98 45 3325 2251 e.eskandarpour@arums.ac.ir Ardabil University of Medical Sciences Iran (Islamic Republic of) Having asthma age between 5-12 years Lack of chronic disability or illness 5 years 12 years Both Failure to complete the course of treatment J45 Asthma Treatment - Drugs Treatment - Drugs Intervention group: Patients in the intervention group will be given 1 to 4 grams of dried thyme leaf powder prepared as a syrup for a week, at a dose of 20 mg / kg every 8 hours, along prednisolone tablets (1 mg / kg, daily, Abureyhan Co.), salbutamol spray (2 puffs every 3 hours by Caspian Tamin Co), theophylline syrup (4 cc every 6 hours by Elixir Co) with routine medical treatment. Control group: Control group will receive 2 cc placebo syrup and prednisolone tablets (1 mg / kg, daily, Abureyhan Co.), salbutamol spray (2 puffs every 3 hours by Caspian Tamin Co), theophylline syrup (4 cc every 6 hours by Elixir Co) with routine medical treatment. Cough. Timepoint: Before and after the intervention. Method of measurement: Medical examination. Fever. Timepoint: Before and after the intervention. Method of measurement: Thermometer. Wheezing. Timepoint: Before and after the intervention. Method of measurement: Medical Examination. Ardabil University of Medical Sciences Approved 2019-08-10 Ethics committee of Ardabil University of Medical Sciences Daneshghah Street Ardabil Ardabil Iran (Islamic Republic of)