<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20200504047294N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2020-06-30</date_registration>
      <primary_sponsor>Bashir Institute Of Health Sciences, Islamabad.</primary_sponsor>
      <public_title>Effect of NMR in university students</public_title>
      <acronym></acronym>
      <scientific_title>Effectiveness of Neuromuscular Re-education (NMR) treatment in improving upper extremity symptoms among Smartphone using university students</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2020-05-11</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>30</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/47695</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization method is simple Draw. Study participants were allocated to two groups, the experimental group (n=15) and the placebo group (n=15), the grouping was completely randomized (Draw), Blinding description: In this study participants are blinded. They only knew they are part of study not knowing to which group they belong moreover both experimental and placebo group treatment was giving on consecutive 3 weekdays.</study_design>
      <phase>N/A</phase>
      <hc_freetext>Condition 1: 1) Neck pain( Forward neck). Condition 2: 2) Musculoskeletal  Pathology of upper limbs. Condition 3: tenosynovitis [de Quervain]. ( texting thumb). Condition 4: Lateral epicondylitis ( tablet elbow).</hc_freetext>
      <i_freetext>Intervention 1: Intervention group:1)Number of participants in group: n=15. 2)Age: 18-25 years. 3)Gender: all females. 4)Mild to moderate symptoms on Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire score.5)Manual Muscle testing score (MMT 0-5) 3 out of 5. 6) this group will be given exercise treatment. Intervention 2: Control group:1)Number of participants in group: n=15.  2)Age: 18-25 years. Gender: all females. 3)Mild to moderate symptoms on Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire score.4)Manual Muscle testing score (MMT 0-5) 3 out of 5. 6) this group will be given placebo treatment.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>No - There is not a plan to make this available</results_IPD_plan>
      <results_IPD_description>Justification or reason for not sharing IPD is "There is no further information"</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Ayesha Siddiqa</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Bashir Institute Of Health Sciences, Near Seri choke, Simly Dam Road,Bara Kahu , Islamabad.</address>
        <city>Islamabad</city>
        <country1>Pakistan</country1>
        <zip>45400</zip>
        <telephone>+92 51 2234217</telephone>
        <email>dr.ayesha368@gmail.com</email>
        <affiliation>Bashir Institute Of Health Sciences, Islamabad.</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Ayesha Siddiqa</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Bashir Institute Of Health Sciences, Near Seri choke, Simly Dam Road,Bara Kahu , Islamabad.</address>
        <city>Islamabad</city>
        <country1>Pakistan</country1>
        <zip>45400</zip>
        <telephone>+92 51 2234217</telephone>
        <email>dr.ayesha368@gmail.com</email>
        <affiliation>Bashir Institute Of Health Sciences, Islamabad.</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Pakistan</country2>
    </countries>
    <criteria>
      <inclusion_criteria>•	Mild to moderate symptoms on DASH score.
•	Excessive use of smart phone device up to more than 3 hours daily.
•	Complains of pains and muscular fatigue mostly in upper extremity.
•	Have headache complain during prolong neck bending</inclusion_criteria>
      <agemin>18 years</agemin>
      <agemax>25 years</agemax>
      <gender>Female</gender>
      <exclusion_criteria>•	History of traumatic injuries.
•	Surgical interventions of the neck or upper limbs.
•	Medical conditions (Diabetic neuropathy, sensory deficits).
•	Chronic diseases such as rheumatoid Arthritis, osteoarthritis, and other connective tissue disorders</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>M54.2</hc_code>
      <hc_code>M79.603</hc_code>
      <hc_code>M65.4</hc_code>
      <hc_code>M77.1</hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword>Cervicalgia</hc_keyword>
      <hc_keyword>Pain in arm, unspecified</hc_keyword>
      <hc_keyword>Radial styloid tenosynovitis [de Quervain]</hc_keyword>
      <hc_keyword>Lateral epicondylitis</hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Treatment - Other</i_code>
      <i_code>Placebo</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention group:1)Number of participants in group: n=15. 2)Age: 18-25 years. 3)Gender: all females. 4)Mild to moderate symptoms on Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire score.5)Manual Muscle testing score (MMT 0-5) 3 out of 5. 6) this group will be given exercise treatment.</i_keyword>
      <i_keyword>Control group:1)Number of participants in group: n=15.  2)Age: 18-25 years. Gender: all females. 3)Mild to moderate symptoms on Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire score.4)Manual Muscle testing score (MMT 0-5) 3 out of 5. 6) this group will be given placebo treatment.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>1)The Disabilities of the Arm, Shoulder and Hand (DASH) Score. Timepoint: before intervention and 4 week after intervention. Method of measurement: 1)  Disabilities of the Arm, Shoulder and Hand (DASH) score percentage.</prim_outcome>
      <prim_outcome>2)  Visual Analog Scale VAS for pain                                                                      . Timepoint: before intervention and 4 week after intervention. Method of measurement: Visual Analog Scale (VAS) for pain level.    0-10.</prim_outcome>
      <prim_outcome>3) muscle Strength in MMT scale for NECK and Upper Extremity muscle. Timepoint: before intervention and 4 week after intervention. Method of measurement: Manual Muscle TEST ( MMT ) 0-5 scale for muscle strength of neck and U.E.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome></sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Bashir Institute Of Health Sciences, Islamabad.</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2020-04-24</approval_date>
        <contact_name>Ethical Committee for Clinical Research (ECCR), Bashir Institute of Health Sciences (BIHS).</contact_name>
        <contact_address>Bashir Medical Institute, Simly Dam Road,Near Seri choke,Bara khau , Islamabad Islamabad Punjab Pakistan</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
