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IRCT20200418047121N1 IRCT 2020-05-01 Kermanshah University of Medical Sciences Study the effectiveness of concomitant use of vitamin C, metformin, azithromycin and doxycycline on improving patients with COVID-19 Study of the effectiveness of concomitant use of vitamin C, metformin, azithromycin and doxycycline on improving patients with COVID-19 2020-05-09 anticipated 40 Complete https://irct.ir/trial/47578 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Using the random number table, patients are divided into two groups of 20. Each patient is assigned a 4-digit code based on the random number table, Based on the right number of patients code, the patients are divided into two groups. Patients whose last digit is 0, 2, 4, 6, 8 will be assigned to the intervention group and patients whose last digit is 1,3,5, 7, 9 will be assigned to the control group. 3 COVID-19. Intervention 1: The intervention group will receive 250 mg of azithromycin daily for up to five days, 100 mg of doxycycline twice daily, 1.5 g of vitamin C every 6 hours, and 500 mg of metformin daily for one week. Intervention 2: The control group will receive the usual medication. Yes - There is a plan to make this available What will be shared: The main outcomes of the study will be shared. When: 3 months To whom: If requested, results will be made available to other academic researchers Conditions: Collected data is confidential and will not be shared with anyone else Where to obtain: Send E-mail to the responsible for the update to get the documentation How to obtain: Documentation will be emailed within a 15-day timeframe Comments:
public Dr. Kamran Mansouri
Medical Biology Research Center, Parastar Boulevard
Kermanshah Iran (Islamic Republic of) 6714415185 +98 83 3427 6473 kamranmansouri@gmail.com Kermanshah University of Medical Sciences scientific Dr. Faizullah Mansouri
Emam Hospital, Parastar Boulevard
Kermanshah Iran (Islamic Republic of) 6715847141 +98 83 3427 6306 F_mansoury@ yahoo.com Kermanshah University of Medical Sciences Iran (Islamic Republic of) Patients with coronavirus have mild to moderate viral infections diagnosed by an infectious disease specialist no limit no limit Both Patients with severe lung involvement and severe respiratory symptoms patients with G6PD deficiency U07.1 COVID-19, virus identified Treatment - Drugs Treatment - Drugs The intervention group will receive 250 mg of azithromycin daily for up to five days, 100 mg of doxycycline twice daily, 1.5 g of vitamin C every 6 hours, and 500 mg of metformin daily for one week. The control group will receive the usual medication. Disease recovery. Timepoint: The beginning of the study and the end of the study. Method of measurement: Based on laboratory and imaging criteria. Kermanshah University of Medical Sciences Approved 2020-04-11 Ethics committee of Kermanshah University of Medical Sciences Building No.2, Shahid Beheshti, Vice Chancellor for Research Affairs, Kermanshah University of Medical Sciences Kermanshah Kermanshah Iran (Islamic Republic of)