IRCT20200423047176N1 IRCT 2020-04-29 Islamic Azad University Effectiveness of Yoga Comparing to Amantadine and Commitment Group Therapy in Patients with Multiple Sclerosis ACT Effectiveness of Yoga Comparing to Amantadine and Commitment Group Therapy on Fatigue and Pain and Life Quality in Patients with Multiple Sclerosis 2020-04-27 anticipated 90 Complete https://irct.ir/trial/47463 interventional Randomization: Not randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. 3 MULTIPLE SCLEROSIS. Intervention 1: Intervention Group 1 Yoga Exercises: For 12 weeks and three sessions each week and each session for 75-60 minutes under the supervision of an experienced instructor. Asana (movement) exercises 40-35 minutes including stretching and softening exercises in all muscles of the body, pranayama exercises (breathing) 10-15 minutes including controlling the ratio of inhalation and exhalation, meditation (release) 15-20 minutes on a regular basis and focusing on a topic Special. Intervention 2: Intervention Group 2 Acceptance and Commitment Therapy Group for 12 Weeks a week 60-minute session under the supervision of a specialist who has all six components of treatment including admission, fault, self as field, mindfulness, enlightenment values ​​and commitment in The format of metaphors and exercises was taught. Intervention 3: Intervention group 3 Use of amantadine 100mg twice daily for three months (one every 12 hours). Yes - There is a plan to make this available What will be shared: The data seems to be as clear as possible When: Start access three months after printing the results To whom: Researchers working in universities, scientific and medical centers Conditions: In order to be used for the well-being of patients with MS Conditions: No change of content Where to obtain: I am Raheleh Rezaian Langroudi by e-mail r.r1351@yahoo.com or Hamadan Branch of Azad University, Department of Medical Sciences How to obtain: send mail Comments: