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IRCT20200225046612N1 IRCT 2020-05-01 Kermanshah University of Medical Sciences Investigating the effect of commiphora mukul on osteoarthritis of the knee Evaluation of the effectiveness of Iranian traditional medicine product based on commiphora mukul on patients with osteoarthritis of the knee compared to placebo 2020-05-21 anticipated 70 Complete https://irct.ir/trial/47391 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: The study will be conducted randomly using simple randomization Based on the table of random numbers will be in one of the two groups of Intervention numbers (35 people) and placebo (35 people), Blinding description: In order to blind the study, the droplets are encoded by a person other than the researcher in the same packages as A and B before the study begins.And all patients are asked to bring their previous drops with them in each visit. Patients and researchers are unaware of the type of medication until the end of the study. 3 Knee osteoartritis. Intervention 1: Intervention group: twice a day for two months from the extract of commiphora mukul plant, which is prepared by Badrang teb Kuhistan, affiliated to the Science and Technology Park of the Ministry of Science and Technology, according to scientific standards, under the supervision of a traditional pharmacy specialist at a dose of 15 ml. Intervention 2: Control group: Patients with a dose of 15 cc for two months are given a placebo that is similar to the intervention drug. Yes - There is a plan to make this available What will be shared: Total data When: 6 months after printing To whom: University and industrial institutions Conditions: Treatment Where to obtain: Abolghasem Mirzaei Kermanshah University of Medical Sciences How to obtain: By email Comments:
public Mirzaie abolghasem
- Shahid Shiroudi Boulevard - Daneshgah Street - Nurse Boulevard - Faculty of Pharmac
Kermanshah Iran (Islamic Republic of) 6714415153 0098838214440 abolghasem.mirzaie@gmail.com Kermanshah University of Medical Sciences scientific Farzaei mohammad hossain
Shahid Shiroodi Boulevard - Daneshgah Street - Nurse Boulevard - School of Pharmacy
Kermanshah Iran (Islamic Republic of) 6714415153 +98 83 3427 6489 mh.farzaei@gmail.com Kermanshah University of Medical Sciences Iran (Islamic Republic of) Iran (Islamic Republic of) Patients should be between 40 and 70 years old, Diagnosis of knee osteoarthritis based on the diagnostic criteria of American College of Rheumatology and confirmation of knee osteoarthritis by a rheumatologist using radiography and kellgren lawrence criteria The presence of moderate knee pain in the last 24 hours so that according to the Visual Analogue Scale (VAS) the pain is between 4 to 7 cm 40 years 70 years Both .Cancer or serious illness Symptoms or history of liver or kidney failure Treatment with oral corticosteroids in the last 4 weeks or Corticosteroid injections in the last 6 months fever Consumption of any type of medicinal plant Allergy to commiphora Lack of willingness to continue participating in the study Nonconformity with the study protocol See any side effects Lack of nutritional supplementation and painkillers M15.0 Primary generalized osteoarthrosis Treatment - Drugs Placebo Intervention group: twice a day for two months from the extract of commiphora mukul plant, which is prepared by Badrang teb Kuhistan, affiliated to the Science and Technology Park of the Ministry of Science and Technology, according to scientific standards, under the supervision of a traditional pharmacy specialist at a dose of 15 ml. Control group: Patients with a dose of 15 cc for two months are given a placebo that is similar to the intervention drug The severity of the pain. Timepoint: Before the intervention and the next two months. Method of measurement: VAS questionnair. Inability to function. Timepoint: Before the intervention and the next two months. Method of measurement: Koos questionnaire. Quality of Life. Timepoint: Before the intervention and the next two months. Method of measurement: Koos questionnaire. Kermanshah University of Medical Sciences Approved 2020-03-03 Kermanshah University of Medical Sciences Research Ethics Committee Kermanshah - Beheshti Boulevar Kermanshah Kermanshah Iran (Islamic Republic of)