IRCT20120718010324N57 IRCT 2020-06-30 Tabriz University of Medical Sciences The effect of probiotic on mood status and sleep quality in menopausal women The effect of probiotic on mood status and sleep quality in menopausal women: A triple-blind randomised controlled trial 2020-07-21 anticipated 66 Complete https://irct.ir/trial/47177 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: The participants will be assigned into the two intervention groups (probiotic yogurt recipient) and control (ordinary yogurt recipient) by stratified block randomization method (stratification based on the time elapsed passed since the onset of natural menopause; less than 5 years and more than 5 years) with block sizes of 4 and 6 and a 1: 1 allocation ratio. Random sequence will be determined by the person not involved in the sampling and data collection. For Allocation Concealment, the code of yogurt will be written on piece of paper and placed inside the serial numbered envelopes. After obtaining informed consent, the relevant envelope will be opened and the intervention type will be determined, Blinding description: Participants, researchers, data analysts, and outcome assessors will be blinded due to the fact that the code of the packages of yogurt will be inserted in sealed envelopes and random allocation will be done by the person not involved in sampling. The shape, weight and appearance of probiotic or ordinary yogurt packages will be same. 3 Menopause. Intervention 1: Intervention group will consumed 100 grams of yogurt containing probiotics daily for 6 weeks. Intervention 2: Control group will consumed 100 grams of ordinary yogurt daily for 6 weeks. No - There is not a plan to make this available Justification or reason for not sharing IPD is Participant data is confidential