IRCT20120718010324N56 IRCT 2020-06-22 Tabriz University of Medical Sciences Assessing the effect of cervical ripening baloon and evening primrose oil comparing with misoprostol on bishop score and duration of first stage of labor Labor induction with unfavorable cervix; Assessing the effect of cervical ripening balloon and evening primrose oil comparing with misoprostol on bishop score and duration of first stage of labor 2020-06-21 anticipated 90 Complete https://irct.ir/trial/47056 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Participants will be allocated to 3 groups by stratified randomized blocking method (stratification will be based on parity, primiparous in one strata and parity 2 - 4 in another strata) with block sizes of 3 and 6 with a 1: 1: 1 ratio as follows: Group 1: 25 µg of vaginal misoprostol, Group 2: 4000 mg Vaginal capsule of evening primrose oil (EPO) and Group 3: Cervical Ripening Baloon. for Allocation Concealment, the type of intervention will be written on piece of paper and placed inside the serial numbered envelopes. After obtaining informed consent, the relevant envelope will be opened and the intervention will be performed, Blinding description: In order to blind the drugs, two envelopes with the same content will be prepared for each participant, which will contain 4 capsules (EPO or Placebo capsules) and one tablet (Misoprostol or Placebo) and will be packaged in the same way. Envelopes will be coded by another person. About cervical Ripening Baloon, there is no possible for blinding. 3 Labor induction. Intervention 1: Intervention group 1: vaginal capsule evening primrose oil 4000 mg. Intervention 2: Intervention group 2: Double balloon cervical ripening catheter. Intervention 3: Intervention group 3: vaginal tablet misoprostol 25 microgram. Yes - There is a plan to make this available What will be shared: The results of clinical study will be published as article When: Immediately after publishing the results To whom: All researchers Conditions: Scientific using with citation to article Where to obtain: mirghafourvandm@tbzmed.ac.ir How to obtain: Up to one week after communication by email Comments: