<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20200228046632N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2020-03-09</date_registration>
      <primary_sponsor>University of Tehran</primary_sponsor>
      <public_title>The effect of high intensity circuit training on two muscle growth factors</public_title>
      <acronym></acronym>
      <scientific_title>Effect of High-intensity circuit training on serum Myogenin and Myostatin adolescents soccer players</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2018-12-23</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>21</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/46199</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Other, Randomization description: Randomization was performed in this study by a simple method, individually and by lottery method. In this study, subjects were randomly divided into experimental and control groups. Before the intervention, 22 adolescent boys aged 14 to 16 years were selected after completing a physical activity questionnaire and demographic data. The subjects' names were recorded on separate sheets and placed in a draw. After each time the cards were shuffled, one card was randomly assigned to the experimental group and the control group according to the number of each subject, with the individual numbers in the control group. Then, so that the odd numbers in the control group and the even numbers were put in the experimental group. To hide the subject grouping process, we informed each subject by a letter of their group status, Blinding description: In this study, subjects and evaluators of field and laboratory tests were kept blind to study groups. About the subjects, we informed each subject in the form of a confidential letter about all the tasks and their grouping requirements. We reported the status of the subject grouping through the code selected for each group (exercise group (1) and control group (2)) and no group names were recorded in the subjects' letters. Also the field and laboratory receiver tests did not know about the status of the subjects.</study_design>
      <phase>N/A</phase>
      <hc_freetext>Impact of exercise protocol.</hc_freetext>
      <i_freetext>Intervention 1: Exercise group: High-intensity circular exercises. This training protocol consists of 8 stations including 20m sweep, Swedish swim, Scott Jump, Planck Jack, Nordic, Climbers, high Knee, and Burpee. Between each station, the subjects rested for 1 minute in the first 2 weeks and 30 seconds in the following weeks. Subjects performed these exercises 3 times a week for 8 weeks. These exercises were performed in the first four weeks at 80% of the subjects' maximum heart rate. During the second four weeks, subjects were administered 85 to 90% of their maximum heart rate. Intervention 2: Control group: Control group subjects performed their normal football training routine. Subjects in this group, like the training group, performed their soccer training for 8 weeks, 3 sessions a week.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Yes - There is a plan to make this available</results_IPD_plan>
      <results_IPD_description>What will be shared:
All information obtained from biochemical tests of each subject on the basis of individual numbers can be made available to valid researchers.

When:
12 months after publication of research results

To whom:
Authentic academic researchers

Conditions:
For the purpose of follow-up, review and meta-analysis studies

Where to obtain:
University of Tehran - Dr. Mohammad Reza Kurdi

How to obtain:
First, the required documentation for teaching employment at one of the universities approved by the Ministry of Science and Technology of the Islamic Republic of Iran is sent to the following e-mail address: A.ziyaiyan74@ut.ac.ir. The candidate is sent to submit a brief report on how to conduct his / her research. Then, if the researcher in charge of this study, Dr. Mohammad Reza Kurdi agrees, all the information required in a file will be kept confidential, including the names, contact numbers, addresses, and personal information of the selected researcher. This process also takes a week.

Comments:
</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Mohammadreza Kordi</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Faculty of physical education and sport science university of Tehran - between 15th and 16th streets - north Karegar street.</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>1439813117</zip>
        <telephone>+98 21 5388 3017</telephone>
        <email>m.kordi@ut.ac.ir</email>
        <affiliation>University of Tehran</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Mohammadreza Kordi</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Faculty of physical education and sport science university of Tehran - Between 15th and 16th streets - North Karegar street</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>1439813117</zip>
        <telephone>+98 21 5388 3017</telephone>
        <email>m.kordi@ut.ac.ir</email>
        <affiliation>University of Tehran</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>Male gender
Presentation of a cardio-respiratory health certificate by a physician
All subjects are in the same range of puberty (by prediction of the age of peak Height Velocity in the age range of 14 to 14.5 years).</inclusion_criteria>
      <agemin>14 years</agemin>
      <agemax>16 years</agemax>
      <gender>Male</gender>
      <exclusion_criteria>Parents 'or subjects' dissatisfaction with the test
Sports injuries: Muscle rupture, knee ligament rupture
Consumption of any type medication or sport supplement</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code></hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword></hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>N/A</i_code>
      <i_code>N/A</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Exercise group: High-intensity circular exercises. This training protocol consists of 8 stations including 20m sweep, Swedish swim, Scott Jump, Planck Jack, Nordic, Climbers, high Knee, and Burpee. Between each station, the subjects rested for 1 minute in the first 2 weeks and 30 seconds in the following weeks. Subjects performed these exercises 3 times a week for 8 weeks. These exercises were performed in the first four weeks at 80% of the subjects' maximum heart rate. During the second four weeks, subjects were administered 85 to 90% of their maximum heart rate.</i_keyword>
      <i_keyword>Control group: Control group subjects performed their normal football training routine. Subjects in this group, like the training group, performed their soccer training for 8 weeks, 3 sessions a week.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Serum levels of myogenin. Timepoint: During four stages including: rest before intervention, 1 hour after maximal aerobic activity, eight weeks after intervention, and one hour after aerobic activity after 8 weeks of intervention. Method of measurement: Through ELISA KIT of the subjects' serum samples.</prim_outcome>
      <prim_outcome>Serum values of myostatin. Timepoint: During four stages including: rest before intervention, 1 hour after maximal aerobic activity, eight weeks after intervention, and one hour after aerobic activity after 8 weeks of intervention. Method of measurement: Through ELISA KIT of the subjects' serum samples.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome></sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>University of Tehran</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2019-03-12</approval_date>
        <contact_name>Ethics Committee in Research of Faculty of Physical Education and Sport Sciences - University of Teh</contact_name>
        <contact_address>Faculty of physical education and sport science-between 15th and 16th streets- north kargar Tehran Tehran Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
