IRCT20200213046484N1 IRCT 2020-03-06 Iran University of Medical Sciences The effect ofmidazolam and anxiety on amnesia The American Society of Anesthesiologists (ASA) (GA)general anesthesia SpO2 stands for peripheral capillary oxygen saturation blood pressure( BP The effects of different doses of midazolam and preoperative anxiety on retrograde and anterograde amnesia in patients undergoing abdominal laparotomy under general anesthesia 2020-05-21 anticipated 120 Complete https://irct.ir/trial/46115 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Not used, Assignment: Factorial, Purpose: Treatment, Other design features: n our study, 120 patients aged 20 to 60 years at risk of ASA1-2 undergoing non-emergency abdominal laparotomy undergoing GA at Rasoul Akram Hospital were randomly assigned to two groups of 60 high stress subjects after the Amsterdam test. And they will be normal. Then the patients in each group are again divided into three groups of 20 each, Randomization description: In our study, 120 patients aged 20 to 60 years at risk of ASA1-2 undergoing non-emergency abdominal laparotomy undergoing GA at Rasoul Akram Hospital were randomly assigned to two groups of 60 high stress subjects after the Amsterdam test. And they will be normal. Then, patients in each group are again divided into three groups of 20 each. This is done by block randomization. Patients are divided into 3 and 6 blocks, each block having three study groups, Blinding description: The patient and the injector and the registrant are unaware of the type of study, and the study will be a Triple Blind study. 3 anxiety. Intervention 1: Intervention group: : Midazolam .02mg / kg , One dose is injected as a premedication. Intervention 2: Intervention group: Midazolam .04mg / kg ,One dose is injected as a premedication. Intervention 3: Control group:do not take midazolam. Yes - There is a plan to make this available What will be shared: Personal information including patients 'age and sex ,anxiety and the effects of different doses of midazolam on amnesia and hemodynamic variables including blood pressure and heart rate may be disclosed if needed without disclosure and with ethical guidelines When: After publish of the results To whom: Researchers working in academic and scientific institutions Conditions: The Current analysis in medical research subject to ethical standards in studies Where to obtain: Dr. Azadeh Habibi, Rasoul-e-Akram Hospital, Mansouri St., Sattarkhan St., Tehran, IR. 1445613131 Tel,0098216435232 Email:azade_h84@yahoo.com How to obtain: Email request submitted to person Comments: