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IRCT20200205046390N1 IRCT 2020-06-07 Ahvaz University of Medical Sciences Effect of Dexmedetomidine on knee arthroscopic surgery The Effect of intra-articular injection of Dexmedetomidine on pain after knee arthroscopic surgery 2020-01-20 anticipated 70 Complete https://irct.ir/trial/45765 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Individuals are randomly divided into two groups according to the random block permutation method. For example, for blocks of four, we have 6 blocks of AABB, ABAB, BABA, BBAA, BAAB and ABBA which must be n / 4th of these blocks as By placing the sample, the randomization unit is individualized.Random tool is statistical software. Randomization was obtained from www.sealedenevelope.com, Blinding description: Participants are not aware of medication or placebo, despite knowing they were enrolled. The surgeon is also unaware of the contents of the injection in this study because the drug is made available to the outcome assessor. Questionnaire collectors are also unaware of the group of patients receiving the drug. 3 The effect of Dexmedetomidine on analgesia. Intervention 1: Intervention group: In this group of patients, 2 mg / kg dexmedetomidine (Elixir, Iran) together with normal saline 0.9% increased the volume to 20 ml, then using Needle Spinal No. 25, Quincke type is injected into the intra-articular space of the knee by sterile method.Then we will sew the place. Intervention 2: Control group:normal saline 0.9% increased the volume to 20 ml, then using Needle Spinal No. 25, Quincke type is injected into the intra-articular space of the knee by sterile method.Then we will sew the place. Yes - There is a plan to make this available What will be shared: Individual data are shared about the main outcome of the study, including the degree of analgesia and hemodynamic information of patients. When: Start of access period 12 months after printing results To whom: Researchers working in academic institutions Conditions: In order to use the data of this study in other research and to raise awareness in the field of performance Where to obtain: Visit Esfahanian.Y@ajums.ac.ir by email How to obtain: The information will be sent one week after receiving the email Comments:
public Yasaman Esfahanian
No. 87, Phase 2, West 8th Street, Kianpars
Ahwaz Iran (Islamic Republic of) 6155846600 00998 61 33903016 Esfahanian.Y@ajums.ac.ir Ahvaz University of Medical Sciences scientific Yasaman Esfahanian
No. 87, Phase 2,West 8th Street, Kianpars
Ahwaz Iran (Islamic Republic of) 6155846600 +98 61 3390 3016 Esfahanian.Y@ajums.ac.ir Ahvaz University of Medical Sciences Iran (Islamic Republic of) Patients are candidates for knee arthroscopic surgery Patients with ASA class I and II 18 years 60 years Male Renal failure Liver failure Valve and Ischemic Heart disease Hypertension Diabetes Drug users Consumer analgesics within 24 hours before surgery History of infection and malignancy History of Coagulopathy Drug reaction Treatment - Drugs Placebo Intervention group: In this group of patients, 2 mg / kg dexmedetomidine (Elixir, Iran) together with normal saline 0.9% increased the volume to 20 ml, then using Needle Spinal No. 25, Quincke type is injected into the intra-articular space of the knee by sterile method.Then we will sew the place. Control group:normal saline 0.9% increased the volume to 20 ml, then using Needle Spinal No. 25, Quincke type is injected into the intra-articular space of the knee by sterile method.Then we will sew the place. Pain. Timepoint: Postoperative pain severity was assessed at 1, 2, 4, 8, 16, 24 hour after injection. Method of measurement: Visual Analogue Scale criterion (from 0 painless to 10 most painful). Time to receive the first analgesic. Timepoint: During the 24 hours after the operation. Method of measurement: Minutes. Total analgesics consumption. Timepoint: During the 24 hours after the operation. Method of measurement: milligram. Ahvaz University of Medical Sciences Approved 2020-01-17 Ethics committee of Ahvaz Jundishapur University of Medical Sciences No. 87, Phase 2, West 8th Street, Kianpars Ahwaz Khouzestan Iran (Islamic Republic of)