IRCT20130311012782N39 IRCT 2020-02-22 Esfahan University of Medical Sciences Comparison of the effect of adding dexmedetomidine to morphine on duration of mechanical ventilation and heart rate and hypertension in open heart surgery Comparison effect of Morphine and dexmedtomidine infusion on intubation time and hemodynamic parameters in patients undergone coronary artery bypass surgery who admitted in Intensive Care Unit 2020-04-02 anticipated 70 Complete https://irct.ir/trial/45764 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: In this study, 70 patients with inclusion criteria were divided into two groups of 35 using Random Allocation Software. At first the total sample size is entered into the software and in the next section the number of study groups is entered. Output of Software includes a list that distributes participants from 1 to 70 randomly into two groups. Patients are divided into two groups according to the time of referral in order to reach the required sample size in each group, Blinding description: This study is a double blind study and patients and researchers are unaware of the type of drug being administered. The drugs are provided by a staff member of the operating room who is not in the study on similar, coded syringes and provided to the project administrator for injection. 3 Coronary Artery Bypass Graft Surgery. Intervention 1: Intervention group: Dexmedetomidine recipient 0.25 μg / kg / hour, plus morphine 0.25 mg / kg/ hour in 50 ml volume upon admission to intensive care unit. Intervention 2: Control group: Morphine recipient 0.25 μg / kg / hour, plus normal saline in 50 ml volume upon admission to intensive care unit. No - There is not a plan to make this available Justification or reason for not sharing IPD is The project is owned by the state agency and cannot be published.