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IRCT138706231245N1 IRCT 2009-04-19 Mazandaran University of Medical Sciences The treatment of Acne Vulgaris Comparison of theraputic effects of topical Azithromycin , Erythromycin and Clindamycin for the treatment of acne vulgaris 2006-04-30 anticipated 96 Complete https://irct.ir/trial/457 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Other, Purpose: Treatment. 3 Acne Vulgaris. Intervention 1: Topical Azithromycin, 2% alcohol solution, two times daily on the clean skin for 3 months. Intervention 2: Topical Erythromycin and Clindamycin, 2% alcohol solution, two times daily on the clean skin for 3 months.
public Ravanbakhsh Esmaeeli
No. 2 University building. Moallem square
Sari Iran (Islamic Republic of) 4817844718 +98 15 1325 7230 Esmaeeli2003@yahoo.com Mazandaran University of Medical Sciences(Vice-chacellor for Research) scientific Zohreh Hajheidari
NO. 2 University building, Moallem square
Sari Iran (Islamic Republic of) 4817844718 +98 15 1325 7230 zhajheidari@mazums.ac.ir Mazandaran University of Medical Sciences(Vice - chancellor for Research) Iran (Islamic Republic of) Inclusion criteria: Presence of mild to moderate Acne Vulgaris (up to 10 comedons, papular and/or pustular lesions). Exclusion criteria: pregnant and breast feeding women, children younger than 10 years old, severe cases of acne (existence of nodules and cysts), receiving anti acne during four weeks prior to study, taking acne creating drugs such as oral or local steroids, vitamin B12, anticonvulsive drugs. 10 years 80 years Both L70.0 Acne vulgaris Treatment - Drugs Treatment - Drugs Topical Azithromycin, 2% alcohol solution, two times daily on the clean skin for 3 months Topical Erythromycin and Clindamycin, 2% alcohol solution, two times daily on the clean skin for 3 months Inflammatory and noninflammatory lesions. Timepoint: Baseline and after 2,4,8, and 12 weeks. Method of measurement: counting lesions using manual lens. Reduction of lesions inflammatory and noninflammatory. Timepoint: Baseline and after 2, 4, 6, and 8 weeks. Method of measurement: ASI formula and total count rate. Mazandaran University of Medical Sciences Approved 2007-04-30 Mazndaran University of Medical Sciences (Vice-chancellor for Research) No. 2 University building, Moallem square Sari Iran (Islamic Republic of)